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  • Sialogogue and Anti Sialogogue

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    Putri Farahmida
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    Anti-sialogogues are drugs that decrease excessive salivation. They can act locally through astringents or systemically through mechanisms like blocking cholinergic receptors or autonomic ganglia. Ptyalism is excessive saliva secretion that can be caused by physiological factors like pregnancy or pathological issues in the CNS, endocrine system, or oral cavity. It may also be induced by drugs like cholinomimetics. Treatment depends on the underlying cause and may involve speech therapy, medications, radiation therapy or surgery.

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    91796635 Sialogogue and Anti Sialogogue

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    Anti-sialogogues are drugs that decrease excessive salivation. They can act locally through astringents or systemically through mechanisms like blocking cholinergic receptors or autonomic ganglia. Ptyalism is excessive saliva secretion that can be caused by physiological factors like pregnancy or pathological issues in the CNS, endocrine system, or oral cavity. It may also be induced by drugs like cholinomimetics. Treatment depends on the underlying cause and may involve speech therapy, medications, radiation therapy or surgery.

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    886 views6 pages

    Sialogogue and Anti Sialogogue

    Uploaded by

    Putri Farahmida
    Anti-sialogogues are drugs that decrease excessive salivation. They can act locally through astringents or systemically through mechanisms like blocking cholinergic receptors or autonomic ganglia. Ptyalism is excessive saliva secretion that can be caused by physiological factors like pregnancy or pathological issues in the CNS, endocrine system, or oral cavity. It may also be induced by drugs like cholinomimetics. Treatment depends on the underlying cause and may involve speech therapy, medications, radiation therapy or surgery.

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    ANTI-SIALOGOGUE

    #Definition …..
    Anti-Sialogogues are the agents or
    drugs which are used to decreased
    salivation due to excessive
    salivation in mouth or any other
    reasons.
    Classification of anti-Sialogogues

    ANTI-SAIALOGOGUE

    LOCALLY ACTING SYSTEMICALLY ACTING

    CNS DEPRESSANTS
    e.g. ASTRINGENTS CHOLINERGIC ANTAGONIST e.g. Morphine,
    Opium.

    ANTI-MUSCARINIC
    e.g.. Atropine,
    Scopolamine

    ANTI-NICOTINIC

    AUTONOMIC GANGLIONIC BLOCKER


    e.g. Hexamittonium
    PTYALISM
    #Definition ……
    It is a clinical
    condition
    characterized by
    excessive secretion
    of saliva from major
    or minor salivary
    glands of oral region.
    CAUSES OF PTYALISMS
    A. Pathos-physiological causes….
    a) Physiological causes….
    *Pregnancy,
    *Malnutrition,
    *Menstruation,
    b) Pathological causes….
    1) CNS causes….
    *Bell’s palsy,
    *Hysteria,
    *Rabies,
    *Stroke,
    *Parkinson’s disease.
    CAUSES OF PTYALISMS …(continue)

    2) Endocrine causes….
    *Exophthalmia goiter.
    3) GIT causes….
    *Nausea and vomiting,
    *Gastro esophageal reflex.
    4) Oral causes….
    *Stomatitis,
    *ANUG.
    B. Drug induced…..
    a)Cholinomimetic agent…..
    *Pilocarpine,
    *Neostigmine,
    *Physostigmine.
    b)Others agent….
    *Mercury,
    *Iodine.
    MANAGEMENT OF PTYALISMS

    Management of ptyalism depends upon the


    causes….
     Speech therapy

     Behavioral therapy

     Radiation therapy

     Medications

     Surgery

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