GROUP 9

 Dwi Ajeng Setyoningrum (P17220181009)

 Aprilia Dwi Nisa Anjani (P17220181019)
 Veren Aurelli Nasywa (P17220183034)
 Faulya Isro’atul Chandya (P17220183037)
Many persons
believe that they
lived an
unhappy
childhood
 Our childhood was
stolen

We’ve grown
up before our
times We’ve been
deprived of
our
childhood
 I WILL ASK YOU
JUST ONE SIMPLE
QUESTION
HAVE YOU EVER MET A
CHILD WITH PROGERIA?
IF YOU DID, YOU WERE
GOING TO FEEL THAT
YOU ARE FORTUNATE
AND YOU WILL DISCOVER
THE TRUE IDENTITY OF
THE CHILDHOOD
PROGERIA
Presentation Definition of Progeria
What is Progeria?

Materials
Causes of Progeria
How is the causes of Progeria?

Symptoms of Progeria
What are the symptoms of Progeria?

Treatment Progeria

Outlook Progeria
 What is Progeria?
Progeria is a rare genetic condition that causes a person to
age prematurely.
Children with progeria appear healthy, but by the age of 2
years, they look as if they have become old too fast.

There are different types of progeria, but the classic type is know as
Hutchinson-Gilford Progeria Syndrome (HGPS)
It is caused a mutation in the lamin A (LMNA) gene, and it involves
severe hardening of the arteries from a young age.
 How is the causes of
Progeria?

The causes of progeria is genetik.

Most children with progeria have mutation on the gene that encodes for
lamin A, a protein that hold the nucleus of the cell together. This protein is
also known as progerin.
The defective protein is tought to make the nucleus unstable, this instability makes
cells more likely to die younger leading to the symptoms of progeria
 What are the symptoms of
Progeria? Visible venis
Stroke
Limited growth and short
Narow, wrinkled, or shrunken
stature
face
Lack of body fat and muscle A head that is large compared
with the body

Loss of hair, including A small jaw bone

eyelashes and eyebrows Slow and abnormal tooth development
A high-pitched voice
Early signs of skin aging,
including thin skin Limited range of motion and possible hip dislocation
Generalized atherosclerosis, leading to cardiovascular and heart
Stiffnes in the joints disease
 Treatments Progeria
3. Undergoing heart surgery to
slow down heart disease

1. Heart health is critical for people

with progeria, so the doctor may
prescribe statins, nitroglycerin for
angina, and routine therapy for 4. Sunscreen is important for
congestive hear failure protecting the skin, and padding
in shoes can help minimize
discomfort caused by a lack of fat
2. Eating healthily and padding on the body
getting regular exercise
 OUTLOOK PROGERIA
Around the world, 134
In children with progeria, genetic
children are thougt to have
factors increase the risk of developing
progeria across 46 countries.
progressive heart disease from an early
Thirty years ago, little was
age.
known about the cause of progeria,
This increased risk of heart
in 20003 a progeria gene was
disease means that life expectancy is
discovered.
normally between 8 years and 21 years,
This has given hope that a
with an average of 14 years
cure might one day be found
SPECIAL PEOPLE
WITH
SPECIAL HEART
ADALIA ROSE

Birthday : December 10, 2006

Nationality
: American
Age : 13 Years
Sun Sign : Sagittarius
Born In : Round Rock, Texas, United
States
Famous As : YouTuber
SAM BERNS
Born Sampson Gordon Berns

October 23, 1996

Providence, Rhode Island, U.S.
Died January 10, 2014 (aged 17)
Foxborough, Massachusetts, U.S.

Cause of death Complications from Progeria

Nationality American
Education Foxborough High School
Occupation Activist
Known for HBO documentary on progeria, spreading
progeria awareness
THANK YOU