bumps (papules) frequently found on forehead and chin of those with acne.
• Comedonal acne is a pattern of acne in
which most lessions are comedones • Comedonal acne most often affects forehead and chin • Blackheads (open comedones) appear as dark brown/black dots at the surface of the pore. • Blackheads are often found on the nose, but can also appear on other areas of the face and body.
• Whiteheads (closed comedones) are small, 1-
2mm bumps in the skin. • Whiteheads are located deeper in the pore with only a microscopic opening to the skin surface. Since the air cannot reach the follicle, the material is not oxidized and remains white or has the appearance of being “closed” • Comedones arise when cells lining the sebaceous duct proliferate and there is increased sebum production • A comedo is formed by the debris blocking the sebaceous duct and hair follicle. And comedones also involve inflammation. • Salicylic acid is derived from willow bark • Salicylic acid is FDA approved anti acne medical ingredient. • This is the best ingredient for the treatment for the treatment of clogged pores. • Salicylic acid is “fat-loving” or lipophilic beta hydroxyl acid. • Salicylic acid able to penetrate into the oil gland makes it highly effective at binding to and melting the keratin plugs that clog the skin pores(keratolytic). • Salicylic acid speeds up cell turn over rate • It exfoliates, help the skin to shed dead skin cells more effectively Anti-acne effects • Salicylic acid destroys the P.acnes bacteria • Salicylic acid can help reduce redness, acne inflammation, and swelling • Because oil solubility, salicylic acid can penetrate and unclog pores Side effects • Salicylic acid can irritate or make dry skin for sensitive skin or who overuse it
OnabotulinumtoxinA 100 U Significantly Improves All Idiopathic Overactive Bladder Symptoms and Quality of Life in Patients With Overactive Bladder and Urinary Incontinence_ a Randomised, Double-Blind, Placebo-Controlled Trial