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Care and Maintenance

of GP Contact Lens

Lecture 5L4

Published in Australia by
The International Association of Contact Lens Educators
Version:
SecondEdition 2011
2012-May-10
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IACLE CONTACT LENS COURSE

Published in Australia by
The International Association of Contact Lens Educators

Revised Edition 2011

The International Association of Contact Lens Educators 2000-2011


All rights reserved. No part of this publication may be reproduced, stored in a
retrieval system, or transmitted, in any form or by any means, without the prior
permission, in writing, of:
The International Association of Contact Lens Educators
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Australia

Email: iacle@iacle.org
SPONSORS

Development and delivery of contact lens education by IACLE is supported


through educational grants and in-kind contributions

Industry
Supporters

Major In-Kind
Supporters
CONTRIBUTORS

Care and Maintenance of GP Contact Lens


Gina Sorbara, OD, MS, FAAO

Rashmi Mahajan, BOptom

Lewis Williams, AQIT(Optom), MOptom, PhD

For a complete list of acknowledgements please see our website:


www.iacle.org
CONTACT LENS DEPOSITS
LENS MATERIAL: GP CLs

• GP CLs are different:


–  charged sites   water or deposit binding
– no net overall charge

–  matrix porosity

• Some contaminants soluble in GP materials


– can form deposits on or in CLs

• GP CL deposits take  time to appear &  more slowly than on other CLs
– lipid deposits can occur on & in GP CLs
– normally, deposits of lipid-calcium complexes do not occur on GP CLs
CONTACT LENS DEPOSITS
LENS MATERIAL: GP CLs

• GP CLs still susceptible to tear components


– presence of pDMS in siloxane acrylate (SA) materials  relatively
hydrophobic surfaces with lipophilic tendencies
– hydrophilic monomers (e.g. methacrylic acid) added to  CL
wettability
•  –ve charged surfaces
•  protein deposition follows

• Later, fluorine (F) added  fluoro-siloxane acrylate CLs


(FSAs):
• O2 permeability,  wettability,  spoilage rates.
• still susceptible to lipid deposits
CONTACT LENS CARE
FDA HYDROPHOBIC LENS GROUPS
(Stone [2007])

• Group 1 No silicon or fluorine content

• Group 2 Contains silicon but no fluorine


focon stem

• Group 3 Contains silicon & fluorine

• Group 4 Contains fluorine but no silicon

5L1-8
CONTACT LENS MATERIALS
METHYLMETHACRYLATE (MMA) & pMMA

Water does not & cannot


monopolize charged binding
sites in lens materials – other
charged species, especially if PMMA (simplified)
they too are small molecularly,
can bind as easily or more easily
PMMA water content is <1%
CONTACT LENS MATERIALS
SA MONOMERS SIMPLIFIED

Beginning of
substitution
CONTACT LENS MATERIALS
FSA MONOMERS SIMPLIFIED

Beginning of substitution
CONTACT LENS MATERIALS
pDMS (IN SiHy & GP CLs)
GP CONTACT LENS MATERIALS
‘DRY SPOT’ BEFORE TEAR BREAK-UP
Hydrophilic aspects
AIR (hydrophobic)
Tear Film Fluoroalkyls (3X)
Notional lens surface

polyDiMethylSiloxanes

Lens matrix
PMMA
GP CONTACT LENS MATERIALS
‘DRY SPOT’ AFTER TEAR BREAK-UP
Hydrophobic aspects
AIR (hydrophobic)

Fluoroalkyls (3X)
Notional lens surface

polyDiMethylSiloxanes

Lens matrix PMMA


CHARACTERISTICS OF GP
CL MATERIALS

Hydrophobicity:
• Siloxane, e.g. pDMS, SA, or FSA polymers   O2 but are
hydrophobic & lipophilic
–  CL wettability   lubricity   lid traction   lens movement
 comfort & ↕ vision
– if CL surface-hydrophobic & lipophilic surfaces   lipids, 
proteins, & other tear film components & contaminants (drying may
 deposition rates further)
– treated  wettability but in the long-term, treatment may not
endure prolonged & repeated lens cleaning by rubbing
CHARACTERISTICS OF GP CL
LENS MATERIALS continued...

Pore Size
• GP CL’s small pore size (<10 nm – see notes)  most deposits
cannot penetrate lens matrix & therefore tend to remain on surface

• GP multipurpose solutions (GP MPSs) contain antimicrobial agents


at higher concentrations than in SCL or SiHy CL care regimens. This
is possible because GPs are typically non-ionic, have small pore
sizes, & negligible water content. Disinfectants do not penetrate the
lens matrix & adsorbed preservatives can be easily rinsed off the
lens surface (Luensmann, 2009)
CHARACTERISTICS OF GP CL
LENS MATERIALS continued...

Surface Chemistry
• Surface chemistry of GP CLs is complex. Can be influenced
further by environment, e.g. hydrophilic (normal tear film) or
hydrophobic (dry spots  deposits/surface contamination)
– exposure to inappropriate LCPs or excessive polishing during
manufacture ( localized heating) can  wettability & other
properties permanently
– FSA materials can be plasma treated to  their wettability
• surface treatment may not last the life of the CL
• surface failure may define CL ‘end-of-life’
GP CL MATERIALS

• Most modern GP CLs are FSA polymers although SA


CLs are still in use
– GP-specific LCPs are required
– unlike single rôle SCL disinfecting solutions, GP disinfecting
solutions  disinfection &  wettability
– however, fundamentally, GP lens care goals are the same as for
other CLs

• Generally, GP LCPs should not be used on SCL or SiHy


CLs
GP CL CARE & MAINTENANCE
BENEFITS

• Although GP CLs are less deposit-prone than many other


types of CLs, proper lens care is still the key to successful
wear because it:
–  further deposit accumulation

–  microbial contamination ( organism adherence)

–  lens wettability

–  comfort & vision during CL wear

–  lens life
GP CLs
ADVANTAGES

• MK rates in GP CL wearers is lower than for Hy & SiHy


CLs
– GPs: 1-1.5 per 10,000
– Hy CLs: 3.5 per 10,000 (20 per 10,000 in EW)
– DW GP CLs have lowest risk
– SiHy CLs have rates similar to Hy CLs

•  CLPC rate
•  binding of Pseudomonas aeruginosa & Acanthamoeba
spp.
GP CL MATERIALS
DEPOSITS

GP materials containing pDMS or silanes have a net –ve


charge that attract protein deposits (see photo) & bind
deposits more tightly
– deposits bind to dry spots
on lens surface & form
layers appearing as a dull,
non-elevated coating
– lipophilic tendencies of such
materials can  lipid
5L52499-93
deposits as well
GP CL MATERIALS
DEPOSITS

GP materials containing fluorine (e.g. FSAs) are less


susceptible to protein deposits &   surface wettability

– deposits bind to dry spots on


lens surface & form layers
appearing as a dull, non-
elevated coating
– lipophilic tendencies of such
materials can  lipid deposits
5L52499-93
as well
GP CL DEPOSITS:
LIPIDS
• GP CL lipid deposits appear spotty, ‘pearlescent’, or ‘soft & shiny’
(see diagram)
– sometimes, a film may form
– lipid deposits usually form over a non-wetting area of CL
– the deposits  irregular, raised, less-wettable surface   TBUT

• Lipid deposits easily removed by rubbing with a surfactant cleaner


– if extensive, an alcohol-based cleaner required

• Generally, patients are asymptomatic

5L8B-15
GP CL DEPOSITS:
LIPIDS

• Incubated, unworn CLs show SA CLs accumulate 2-3X the lipid of SCLs (SiHy
CLs not tested in this study)

• Lipids bind to surface of GP CLs   hydrophobicity  protein deposition


over the lipid layer
– this lipid-protein coating alters subsequent lipid-protein deposition
• It has been shown that lipid (but GPs still < Hy CLs) was apparent on worn
GP CLs with or without surface treatment
– the amount of lipid appeared to be independent of:
• the material used
• the presence or absence of surface treatment
– some differences in lipid layer patterns were noted between materials
GP CL DEPOSITS:
PROTEINS

• Appearance: hard, matte, often granular &


invariably   CL wettability
– deposits are more conspicuous after tear film
break-up or drying (top picture)
– denatured protein deposits appear as dull,
non-elevated films, sheets, or plaque (see
5L51648-91
picture)
• Can be difficult to remove. A cleaning pad or CL
polishing compound (e.g. Xpal) may be required
– lens replacement (<annual) is preferable
before this type & amount of deposit develops
• Protein deposits are likely to  comfort and may
 CLPC and/or corneal staining
5L50452-93
DEPOSIT RESISTANCE
LOW/MODERATE DK vs HIGH DK

Overall Deposits: GP EW
3-12 Months • In a study of low, moderate, & high Dk
Deposits* (0-4)
4 GP CLs (same manufacturer) for up to 1
year, similar levels of deposition were
3 found for all materials
– true for DW provided CLs cleaned
2 daily
– even in EW, no clinically significant
0.9(SD: 0.6)
1 0.8 (SD: 0.7) deposit differences found between
materials
0 – rate of deposit  also similar
Low/Mod Dk High Dk
*median (IQR )
GP CL CARE
PRODUCT CATEGORIES
• Cleaners :
– there are two types of ‘cleaner’:
• daily surfactant
• protein removers (supplied in tablet or liquid form)
• Disinfecting/Soaking and Wetting Solutions:
– sometimes also referred to as conditioning solutions
– can be classified as multipurpose (MPS) because they fulfill the
functions of disinfection, soaking, & wetting
• Lubricants:
– these are in-eye products intended for instillation while the CLs
are being worn. They re-wet, cushion, & rehydrate the CL in situ
GP CONTACT LENSES
NON-WETTING
• Failure of GP CLs to wet can be the result of:
– deposits
Non-wetting GP CL surface
– poor manufacturing practices - ‘burning’ the
lens surface resulting in localized non-wetting
areas
– residual polishing compound leading to local
areas of hydrophobicity*
– surface contamination by make-up, hand
lotions, hairspray, oils, soaps, finger grease,
5L51783-93 etc. leading to non-wetting areas on GP CLs
GP CL CARE
CLEANING

• Surfactant cleaning:
– surfactant cleaners for GP CLs similar to SCL
counterparts
– alcohol-based cleaners (increasingly uncommon)
well suited to GP CLs that acquire lipid deposits.
• alcohol-based cleaners must be rinsed from
lens surface promptly & thoroughly as they
can alter lens parameters if allowed to
remain on GP CLs
– some cleaners contain ‘abrasive’ particulate
matter that are more effective against adherent
deposits than normal surfactant cleaners
• they have been shown to be safe in normal
use
RGP LENS CARE
CLEANING

• Enzymatic cleaners are available in


tablet (most commonly) or liquid form &
contain either an enzyme or a chemical
agent
– they are recommended for weekly
(sometimes daily) protein removal in
deposit-prone wearers*
• Surface polishing may be necessary for
lenses >12 months old
• A cleaning pad may be effective in
removing some deposits from GP
lenses (opposite)
5L51552-91
GP CLs
CLEANING TECHNIQUE
• GP CLs more susceptible to abrasions & less rigid than
PMMA
–need careful handling
–place CL in the taut palm of the hand
• avoid holding the CL between thumb &
forefinger due to  risk of distortion or lens fracture
5L50170-93

– rub lens with forefinger for  10 seconds


• avoid aggressive pressure & overly vigorous rubbing
• avoid prolonged cleaning with ‘abrasive’ cleaners
• front surface’s first curve junction on high plus CLs is more
difficult to clean due to ‘bridging’ by finger or palm. A ‘ring’
deposit can result
GP LENSES
CLEANING TECHNIQUE

– rinse CL with sterile saline or GP CL MPS


• final lens rinse should be with
manufacturer’s recommended
soaking/storage/conditioning solution

5L50833-94

Caution: If aerosol saline used for rinsing, propellant forms small


bubbles in dispensed saline. These may cause ‘dimple veiling’
(opposite) if the lens is applied to the eye immediately. Dimple veiling
can  blurred vision
GP LENSES
RUB or NO RUB

NO RUB

Fortunately for GP CL wearers, the misguided push


to abandon CL rubbing as the initial step in lens care
was much less aggressive & less successful among
GP CL practitioners & wearers. This means that less
‘undoing’ of this falsehood should be required
GP LENS CARE
DISINFECTION
• GP CL surfaces are just as susceptible to bacterial colonization as
SCLs. Bacteria can also attach to deposits
• As most GP CLs are thermoplastics (heat-deformable), thermal
disinfection not used
• Soaking time usually four hours to overnight
– preservatives used include: thimerosal, phenylmercuric nitrate,
BAK (benzalkonium chloride), CHX (chlorhexidine), a PHX
(polihexanide), or PQ-1 (polyquaternium-1)
• GP care system simplicity & efficacy has resulted in the demise of
the usage of peroxide on GP CLs*
ANTIMICROBIAL AGENTS
MODES OF ACTION
Preservatives & disinfectants

• Damage cell membrane


• Damage cyst wall (encysted species)
• Damage outer cytoplasmic membrane (bacteria) or plasma
membrane (fungi)
• Interference with synthesis of cell wall peptidoglycans
• Alteration/binding/damage/interference with DNA
• Inhibition of synthesis of folic acid, nucleotides, or protein
• Dehydration of cell
• Induction of autolysis
• Potentiation of actions of co-located antimicrobials

5L1-35
GP LENS CARE
WETTING
• Wetting solutions   CL wetting characteristics:
– hydrophobic surface  hydrophilic
–  uniform tear spreading   vision ( optical quality)
–  comfort on insertion ( solution viscosity)
• however, excessive viscosity  temporary  in vision quality
( ‘tear film’ thickness & regularity)

• Wetting agents: PVA (polyvinyl alcohol), PVP (polyvinyl


pyrrolidone), & Polysorbate
• Saliva must never be used to wet a CL because of its microflora
& fauna
• Although less common now, single-purpose GP wetting
solutions have been/are available
SOLUTION PROPERTIES
WETTING (A WETS B)

A
(Tears)
(Wetting Soln.) STLower
(Cleaner)
(MPS) STA STA
W

W
Surface of A

ETTING
ET NG
Surface of B

TI
(CL)
(Cornea) STB STB
STHigher
B
SOLUTION PROPERTIES
SURFACE TENSION (ST)

• STCornea 67.5 to 72 mN/m (Glasgow et al., 1999)

• STTears 42 to 71.5 mN/m (Zhao & Wollmer, 1998, Nagyová & Tiffany, 1999)

• STWater 72.8 mN/m at 20°C

• STPMMA 32 to 49 mN/m (Rankin & Trager, 1970, Goudeau et al., 2000, Zagari et al., 2004)

• STGP 33 to 74 mN/m (solution dependent – from patent submissions)

• STLCPs 34.89 mN/m to 77.13 (Lau & Jones (1999)


GP LENS CARE
WETTING & SOAKING
GP CL Soaking/ Wetting/ Conditioning
• Purpose
– disinfection: wet storage  microbial control of CL storage
conditions &  initial ‘on-eye’ comfort
– wetting: dry storage of GP CLs   wetting,  CL hydration
& flatter BOZR
• maximum in situ lens hydration may also be affected
– storage : better for regular GP CL wearers to wet-store their
CLs*
• Solutions that combine the disinfecting, wetting, & soaking
functions are often called conditioning solutions
GP LENS CARE
WETTING & SOAKING
• Composition of GP CL wetting & soaking
(conditioning) solutions:
– antimicrobial agent(s): disinfect CLs & preserve the solution after initial
opening

– wetting agent:   lens wettability


– viscosity-increasing agent : ‘thicken’ formulation &  stay-time of solution on
CLs after insertion

– buffer system: maintain pH within limits


– osmolality adjusting agents: added to  solution osmolality to isotonicity
with the wearer’s tears* (or near isotonicity)

– pH-adjusting agent(s): set initial solution pH


GP LENS CARE
RINSING
• Rinsing GP CLs after soaking in wetting/soaking (conditioning)
solution usually unnecessary
– insert lens directly into eye
• If vision blurry/variable on lens insertion, change to a less viscous
solution
• If stinging on insertion reported, change to a solution with different
chemistry and/or pH characteristics
• Rinsing with sterile saline before insertion likely to  CL wetting & 
initial comfort
GP LENS CARE
MULTI-PURPOSE SOLUTIONS

• GP CL MPSs combine
cleaning, disinfection, &
soaking functions into a single
bottle
– convenient for user
– sometimes referred to as
one-bottle systems (OBS)
GP LENS CARE
LUBRICATING DROPS

• Lubricating drops  in situ wetting of CLs


– contain surfactants & agent(s)   viscosity
– functions include:
•  comfort
• CL cleaning
•  &  CL wettability
•  friction between lids, CL, & cornea
5L31692-91
•  volume of viscous fluid on the anterior
eye
• removing debris from the PLTF by  CL
movement
GP LENS CARE
LUBRICATING DROPS
Lubricating drops usually contain:
• Preservative (but preservative-free lubricants do exist, usually in unit-
dose form)
– e.g. benzyl alcohol, EDTA, BAK, PQ-1, CHX, PAPB (a PHX),
sodium perborate, or stabilized oxychloro complex
• Viscosity-increasing agent, e.g. methyl cellulose, hydroxypropyl
methyl cellulose (hypromellose), or hydroxyethyl cellulose
• Wetting agent, e.g. polyvinyl alcohol (PVA)
• pH-adjusting agents, e.g. trace amounts of NaOH &/or HCl
• Buffer system to maintain pH, e.g. borate or citrate system
• Osmolality adjusting agent(s), e.g. sodium chloride
OCULAR SYMPTOMATOLOGY

Ocular Symptoms with GP and


SCL wear • Vajdic et al. (1996) found GP CL
% Wearers
25%
23%
& SCL wearers can be
20% differentiated by symptoms, esp.
20%
dryness
16%
15%
13% – data suggests that GP CL
11%
10% 9% wearers complaining of
8%
dryness be  ‘in-eye’
5%
3%
2% 2%
wetting/re-wetting solution
0% (comfort drops) to  comfort
Dryness Redness Grittiness Itchiness Aching
&  symptoms of dryness
SCL GP CL
Vajdic et al. 1996
GP LENS CARE
COMPLICATIONS
• Adverse reactions to GP LCPs are uncommon:
– preservatives not normally absorbed by GP CLs*.
– solution toxicity possible, but small volume on GP CL  the ‘dose’
size
• Punctate staining can occur
• Viscous soaking solutions can   corneal adherence   stay-
time or solution residency
– wearers may complain of blurry/fluctuating vision & a sticky
sensation some time after lens insertion.
– a dehydrated-solution residue may be left on the eyelashes/lid
margins.
GP LENS CARE
COMPLICATIONS
• If a single-purpose CL cleaner enters the eye inadvertently
(finger or CL) an adverse reaction will probably occur
– slit-lamp may reveal punctate (below) or coalesced
staining
GP LENS CARE
STAINING MANAGEMENT

• Remove CL immediately
• Irrigate eye with saline (dilutes, rinses, & lubricates)
• Examine for possible staining with a slit-lamp (previous slide)
• Ocular lubricant may be useful (preservative-free best)
• Epithelial ‘repair’ should be rapid
– monitor eye for 24-48 hours if staining significant
• CLs should not be worn ( recovery rate) until epithelium
appears normal
GP LENS CARE
LENS REPLACEMENT
• Purpose: regular CL replacement = preventative eye care
–  problems  CL deposits
– deposits can:
• irritate lids, especially upper lids
•  deposit build-up   deposit cycle
• act as footholds for micro-organisms
• Schedule:
– GP CLs should be replaced at least annually.
– more often (eg. six-monthly [Woods & Efron, 1996]), if the patient is wearing
EW CLs &/or is a heavy depositor
• CL deposit susceptibility should be considered when prescribing a
replacement regimen
– GP CL programmed replacement schemes do exist
GP LENS CARE
AT DISPENSING

• Upon receipt & before dispensing, GP CLs should be:


– cleaned & soaked in conditioning solution overnight
– after soaking, parameters should be verified
• cleaning & soaking restores lens parameters (many custom-lens
are shipped dry)
• also removes any manufacturing process residues
• lens wettability should be optimal at dispensing time
– confirm lens wettability by observing CL surfaces in vitro (slit-lamp,
stereo microscope, or a magnifier [specular reflection probably best])
GP LENS CARE
TRIAL SET DISINFECTION/STORAGE

• Clean CLs with alcohol-based cleaner immediately after use (Ghajar et


al., 1989)
– with a brief cleaning & a thorough rinsing, GP lens parameter
stability is unaffected by such cleaners (Lowther, 1987)

5L11306-91
GP LENS CARE
TRIAL SET DISINFECTION/STORAGE

• For storage, either:


− container that suspends the CL (opposite) without stress (recommended)
− or, flat-pack with CL placed concave-up to make removal easy
− while wet storage in soaking solution may suit a busy GP CL practice...
− dry storage might be easier to administer in a practice that sees few GP
CL patients
− trial fits with just-wetted, normally dry-stored CLs may be bad GP
CL ‘marketing

• Wet storage necessitates frequent &


scheduled solution changes (14-28 days)

• GP CLs should be cleaned again


immediately before a trial fit

5L40LW1-98
GP LENS CARE
SUMMARY

• Due of their non-absorbent nature, surface properties, rigidity, &


durability, GP CLs are easier to care for than SCLs
• However, as GP CLs are kept in regular use longer than SCLs,
efficacious lens care is essential to successful long-term lens wear
• Wearers should Clean, Rinse, And Disinfectant Lenses Every time
(CRADLE)
• Programmed replacement of GP CLs is an important factor in
maintaining ocular health
– a thorough repolish is probably the next best thing
GP LENS CARE
PRODUCT UPDATES

Due to research advances and changing market conditions,


new LCP releases and older product retirements are
regular events

IACLE is keen to keep its resources up-to-date. Therefore,


we invite members and other interested parties to inform
IACLE of changes in the LCP marketplace
Please forward information to: iacle@iacle.org

As IACLE’s presentations are electronic resources, they


can be updated easily & promptly

IACLE will inform members of resource updates


IACLE RESOURCES
ERRORS, OMISSIONS, IMPROVEMENTS

IACLE also invites users of its resources to help it evolve


and improve them

If you become aware of errors or omissions, or you have


suggestions for improvements, you are invited to submit
them to : iacle@iacle.org for consideration

Contributions incorporated will be acknowledged in the


relevant presentation’s Notes pane(s)
IACLE INDUSTRY SPONSORS
ALL
REFERENCES
USED

(In alphabetical order)


5L1-58
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Refojo M (1983C). In: Lens Deposits – Adapted from the October 1982 meeting of CLAO. CLAO J. 9(2): 173.
Sano K (2000). Contact lens materials and lens contamination. J Jpn CL Soc. 42: 68 – 73.
Schultz CL et al. (2000). Bacterial colonization of rigid gas permeable and hydrogel contact lenses by Staphylococcus
aureus. J Indust Microbiol Biotech 24: 113 – 115.
Sibley M (1983). In: Lens Deposits – Adapted from the October 1982 meeting of CLAO. CLAO J. 9(2): 172.
Tighe B J (2007). Contact lens materials Chap. 3 in: Contact Lenses 5th ed. Phillips A J, Speedwell L. Butterworth
Heinemann, Edinburgh.
Vajdic CM et al. (1996). Do contact lens wearers have more ocular discomfort than spectacle wearers? Invest Ophth Vis
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Assoc. 19(3): 83 - 89.

5L1-60
GP CLs
CLEANERS
• Alcon OPTI-FREE SupraClens • Optikem Intn’l Sereine® Contact Lens
• 
Alcon Opti-Clean II Daily Cleaner Cleaner
• Alcon OPTI-FREE Daily Cleaner • Sauflon Delta GP Cleaner
• ®
Alcon POLYCLENS II Daily Cleaner
• AMO AMO Total Care Cleaner
• Avizor GP Cleaner
• Boston Cleaner
• Boston Advance Lens Cleaner
• Boston Original Formula Cleaner
• Contopharma i-clean! (Miraflow clone?)
• CIBA Vision Miraflow Cleaner (avail.?)
• CIBA Vision Miraflow Extra Strength Cleaner
• EYEYE Crystal Cleaner
• Lobob® Optimum Extra Strength Cleaner Laboratory/Professional Use ONLY
• ®
Lobob Sterile Cleaning Solution
• Boston® Laboratory Lens Cleaner
• MeniCare Plus MPS
• MeniCare Progent
• Menicon Spray & Clean • MeniLab Disinfectant/Cleaner
• Menicon Unique pH
GP LENS CARE
SOAKING SOLUTIONS
Lobob Hard Lens Soaking Solution
GP LENS CARE
CONDITIONING SOLUTIONS

• Boston® Conditioning Solution

• Boston Advance Comfort Formula

Conditioning Solution

• Optikem International Sereine Wetting and

Soaking Solution
GP LENS CARE
WETTING SOLUTIONS

• Lobob Hard Lens Wetting Solutions

• Lobob OPTIMUM Wetting and Rewetting Drop

• MeniCare GP WRW (wetting & rewetting)


GP LENS CARE
MULTI-PURPOSE SOLUTIONS
• Alcon OPTI-FREE® GP Multi-Purpose Solution

• AMO Total Care 1

• Boston Simplus Multi-Action Solution

• Lobob Optimum Cleaning/Disinfecting/Storage Solution

• Menicon Menicare GP CDS (cleaning, disinfecting, soaking) USA only

• Menicon MeniCare Plus

• Menicon Unique-pH Multi-Purpose Solution (formerly Alcon)

• Sauflon delta DSW (disinfecting, soaking, wetting)


GP LENS CARE
LUBRICATING DROPS
• Alcon Clerz® Plus Lens Drops
• Alcon OPTI-FREE® RepleniSH® Rewetting Drops
• AMO blink Contacts Lubricating Eye Drops
• AMO Complete Blink-N-Clean Lens Drops
• Boston® Rewetting Drops
• Menicon Rewetting Drops
GP LENS CARE
PROTEIN REMOVERS

• Alcon OPTI-FREE® SupraClens® Daily Protein Remover

• Boston® One Step Liquid Enzymatic Cleaner


• Menicon Progent (protein remover, disinfectant, intensive cleaner
(For professional use only)
GP LENS CARE
MISCELLANEOUS CARE PRODUCTS

• Boston® Laboratory Cleaner (availability?) (lab-only


product)

• Paragon Fluoro-Solve (availability?) (lab-only product)

• Menicon Progent (protein remover, disinfectant, intensive


cleaner
(For professional use only)
5L1-69

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