Professional Documents
Culture Documents
Life-1 Acute,-3
Serious and-2
Threatening and common and
rare causes
rare causes serious causes
Acute and-4
Chronic or-5
common but
recurrent but Other Causes-6
not serious
:common causes
causes
:DIFFERENTIAL DIAGNOSIS
:Medical history •
Same complaints (help physician to decide referral for -
.tonsillectomy)
.Chronic problems (diabetes mellitus, bronchial asthma) -
Rheumatic fever -
:Surgical history •
.Tonsillectomy -
:Family history
. Same attacks in the family (common in viral sore throat) -
:Drug history
.Use of antibiotics in previous and current sore throat -
.Use of anti-allergics or antibiotics -
.Use of other medications such as inhalers -
.History of immunization -
:Life style
.Diet (cold fl uid may induce sore throat -
.Exercise (dry mouth) -
.Smoking (dry and irritated throat) -
Sex (kissing is a risk factor for infectious mono-nucleosis and -
.homosexuality may lead to HIV infection)
:Hidden agenda
.Other problems (For sick leave) -
.Referral (asking referral for tonsillectomy) -
Asking for antibiotics (patient has used antibiotics and insists for -
.prescribing it again)
:General exam
Temperature: febrile or not (high grade fever could be caused by •
.bacterial sore throat)
.Toxic, drooling of saliva (indicate epiglottitis) •
Blood pressure •
.Barking cough (croup) •
Respiratory distress (upper respiratory obstruction in epiglotitis •
.and croup)
.Stridor (croup or epiglottitis or foreign body) •
Cyanotic (upper airway obstruction) •
:Ear, Nose and Throat Exam
:Tonsil and pharynx appearance
Redness (More severe congestion and red discoloration of the pharynx could be due to •
.bacterial sore throat)
.Exudate (Most likely due to bacterial or infectious mononucleosis) •
.Quinsy (Peri-tonsilar abscess) •
.Cobbling appearance of pharynx (Post-nasal drip) •
.Runny nose (Viral infection) •
.Sinus tenderness (Sinusitis ) •
.Drooling of saliva (Epiglotitis) •
.Greyish pharynx (Diphtheria) •
.White patches (Candida infection) •
.Strawberry tongue (Scarlet fever) •
.Enlarged tonsils (Tonsillitis) •
.Enlarged, tender anterior cervical lymph nodes (Bacterial pharygitis) •
Enlarged, tender posterior cervical lymph nodes (infectious mononucleosis) •
Pharyngitis, visible redness
• Exudate (Most likely due to bacterial or infectious
mononucleosis).
Right sided peritonsillar abscess
Cobbling appearance of pharynx (Post-nasal drip)
thumb printing sign epiglottitis
An adherent, dense, grey pseudo membrane covering the tonsils is
classically seen in diphtheria.
White patches (Candida infection)
The rash of scarlet fever Strawberry tongue is a characteristic of scarlet fever
Result of a group A streptococcus (group A strep) infection, also known as Streptococcus pyogenes.
The signs and symptoms include a sore throat, fever, headaches, swollen lymph nodes,
• Enlarged tonsils (Tonsillitis).
MANAGEMENT
DIAGNOSTIC TESTS
: Definition-
Epiglottitis is the inflammation and swelling of
.the epiglottis and is a medical emergency
Epiglottitis is almost always caused by-
H. influenzae, although Streptococcus
.pneumoniae and Streptococcus pyogenes
Epiglottitis usually occurs in children-
between ages 2 and 8 years, but it may also
.occur in adults
Predisposing Factor
A. Upper respiratory infection
Common Complaints
A. Sudden onset of fever
B. Sudden onset of dysphagia
C. Sudden onset of drooling
D. Sudden onset of muffled voice
Other Signs and Symptoms
A. Respiratory distress
B. Stridor
C. Very ill appearance
PHYSICAL EXAMINATION
:In-hospital treatment
IV fluids .1
Antibiotics; IV antibiotics after physician consultation .2
Blood and epiglottis cultures obtained before starting antibiotics .3
: Drug of choice .4
a. Cefotaxime (Claforan) 100 to 200 mg/ kg/ d every 8 hours IV
b. Ceftriaxone (Rocephin) 50 to 100 mg/ kg/ d every 12 hours IV
c. Ampicillin- sulbactam (Unasyn) 150 mg/ kg/ d every 6 hours IV
d. Amoxicillin- clavulanic acid 100 mg/ kg/ d every 8 hours IV
INDIVIDUAL CONSIDERATIONS
:Epidemiology
Incidence most common in children < 5
years of age
in adults, the most common cause is
:Microbiology
trauma
Streptococcus
:Risk factors
: recent infection, such as
pyogenes
otitis media Staphylococcus aureus
pharyngitis
sinusitis respiratory anaerobes
immunosuppression
RETROPHARYNGEAL ABSCESS
: Diagnostic test-
,Radiographs: obtained with the patient sitting-
demonstrate soft tissue swelling posterior to the pharynx, with a widening of the
.prevertebral soft tissue stripe
Lateral
Marked widening of the pre-vertebral soft tissue
between C2 and C7, with multiple gas foci within at the
C3-C4 level.
MANAGEMENT
Medical-1 Operative-2
empiric intravenous antibiotics surgical drainage
indication indication
abscess < 2.5 cm2 signs of severe respiratory distress
presence of phlegmon well defined abscess > 2.5 cm2
comment
3-Procedural antibiotic choice should target S.
emergent intubation pyogenes, S. aureus, and respiratory
Indication: anaerobes
in patients with signs of significant airway obstruction :
"tripod positioning" e.g., ampicillin-clavulanate and
respiratory distress vancomycin
cyanosis
unable to speak or cough
OTITIS MEDIA
:Acute otitis media AOM •
Moderate to severe bulging of the tympanic
membrane or new onset of otorrhea not due
to acute otitis externa accompanied by acute
signs of illness and signs or symptoms of
middle ear inflammation
DEFINITIONS
: Otitis media with effusion OME •
Middle ear fluid that is not infected. It is also
called serous, secretory, or nonsuppurative
otitis media. OME frequently precedes the
development of AOM or follows its resolution
AOM is primarily an infection of childhood -
It is the most common reason for-
administration of antibiotics in children
It is slightly more common in boys than -
EPIDEMIOLOGY girls
Most cases of AOM occur in young-
children ages 6 to 24 months, with the
incidence of AOM declining significantly
after age 5
The most common bacterial pathogens-
are Streptococcus pneumoniae and
nontypeable Haemophilus influenza,
with Moraxella catarrhalis the third most
RISK FACTORS
Lack of Tobacco
Family
Age Day care breastfeedin smoke and
history
g air pollution
Social and
Race and Limited Season
Pacifier use economic
ethnicity resources (winter)
conditions
Altered host
defenses and
underlying
disease
Children with AOM, particularly infants,
may present with nonspecific symptoms
:and signs
Fever
CLINICAL Irritability
MANIFESTATIONS Headache
Apathy
Disturbed or restless sleep, poor feeding
Anorexia
Vomiting
Diarrhea
CLINICAL
MANIFESTATIONS
N :Observation
Children ≥2 years who are normal hosts (eg,
immune competent, without craniofacial
abnormalities) with mild symptoms and signs and
no otorrhea
When the initial observation strategy is chosen,
caretakers must understand the risks and
benefits, and appropriate follow-up must be
ensured so that antibiotic therapy can be initiated
if symptoms worsen or persist after 48 to 72 hours
Duration of treatment varies with age,
associated clinical features, and antimicrobial
:agent
For amoxicillin, amoxicillin
clavulanate, clarithromycin, oral
DURATION OF :cephalosporins, clindamycin, and levofloxacin
THERAPY Ten days for children <2 years , and children
(of any age) with tympanic membrane
perforation or history of recurrent AOM
Five to seven days for children ≥2 years of age
with intact tympanic membrane and no history
of recurrent AOM
Azithromycin – Five days
Surgery-
Surgical management of AOM can be
divided into the following 3 related
:procedures
MANAGEMEN
T Tympanocentesis
Myringotomy
Myringotomy with insertion of a
ventilating tube
Intratemporal - Perforation of the
tympanic membrane, acute coalescent
mastoiditis, facial nerve palsy, acute
labyrinthitis, petrositis, acute necrotic
otitis, or development of chronic otitis
media
COMPLICATION
S Intracranial - Meningitis, encephalitis,
brain abscess, otitis hydrocephalus,
subarachnoid abscess, subdural abscess,
or sigmoid sinus thrombosis
Systemic - Bacteremia, septic arthritis,
or bacterial endocarditis
CONSULTATION/ REFERRAL
: Allergy-
Seasonal ,Perennial, food-
.related ,drug induced
: Infectious-
Acute-
Chronic-
: R I S K FA C T O R S F O R A L L E R G I C R H I N I T I S
Sleep disturbance -
Impairment of daily activity -
Impairment of work -
Troublesome symptoms -
O CCU PAT I O NA L AL L ER GE NS
:Chemical agent -
paint manufacturer and painter (spray)-
drugs in pharmaceutical worker-
FOOD INDUCED RHINITIS
A.Inspect B.Palpate
.Examine eyes and conjunctivae
a.Palpate face and frontal
a. Tearing; red, swollen eyelids; and allergic shiners
(dark circles under eyes from venous congestion in maxillary sinuses for tenderness
.maxillary sinuses) are seen with allergies
b. Palpebral conjunctiva pale and swollen, bulbar
b.Examine the head and neck for
.conjunctiva is injected .enlarged lymph nodes
.Examine ears, nose, and throat .3
a. Red, dull, bulging, perforated tympanic
.membrane is seen with otitis media D. Percuss
b. Nasal redness, swelling, polyps, and enlarged
turbinates are seen with upper respiratory infection Sinus cavities and mastoid bone
.(URI)
Chest for consolidation .2
Mucosa appears pale blue, and boggy with clear
.discharge in chronic allergy
c. Cobblestone appearance in pharynx, tonsils, and
.adenoids seen in chronic allergies .E. Auscultate heart and lungs
EXAMINATION
General-
: Local ENT examination -
allergic nasal mucosa appear pale or
bluish, boggy with swelling and
.watery discharge
There may be polyp, structural
(septal deviation ,prominent
.turbinate)
Systemic -
INVESTIGATIONS
:Skin Tests -1
it’s a primary tool in the investigation of allergy .its
positive in seasonal rhinitis ,less than 50%in others it
consist of pricking skin ,with special needle few drops of
. allergen
Appearance of wheal and flare in 15-20 min ,the size of
wheal is usually equal or greater than 3mm and
interpreted by positive and negative control
Antihistamine should be discontinued 3-6 days before
test
Intradermal test is rarely used because of extensive
tissue reaction or anaphylaxis
SKIN PRICK TEST
:L A BO RAT O RY T E S T S
:Laboratory tests
.nasal cytology ,eosinophil count in nasal secretion, blood-2
A specific serum immunoglobulin E (IgE) radioallergosorbent-3
test (RAST)
determine presence of Ig E-
Do it for person who can not tolerate skin test -
RAST testing is less sensitive and more expensive than skin-
- A raised IgE level usually confirm allergic constitution but it is neither sensitive
.testing
nor specific.
- Elevated level seen in smoker and parasitic infestation.
TREATMENT
i. Children younger than 5 years: Not ii. Children 6 to 11years: 30 mg twice daily
recommended
ii. Children 5 to 11 years: One spray in each d.Cetirizine HCl (Zyrtec)
nostril twice daily
Adults and children 12 years and older: 5 to 10 mg
iii. Adults: Two sprays per nostril twice daily by mouth daily depending on symptom severity
b.Loratadine (Claritin) 10 mg by mouth daily ii. Zyrtec 5 mg daily for patients with renal or
(adults) hepatic impairment
i. Children younger than 2 years: Not iii. Children 2 to 6 years: 2.5 mg daily
recommended
iv.Children 6 to 11 years: 5 to 10 mg (1– 2
ii. Children 2 to 5 years: 5 mg daily teaspoons) by mouth daily depending on symptom
iii. Children 6 years and older: 10 mg daily severity
MONTELUKAST - 2
:Montelukast ( Singulair)
(SINGUL AIR)
Not recommended for children
younger than 6 months
i. Children 6 to 23 months: One 4-
mg granule packet
ii. Children 2 to 5 years: One 4-mg
chewable tablet or granule packet
iii. Children 6 to 14 years: One 5-
mg tablet
iv. Children older than 15 years and
adults: One 10-mg tablet daily
STEROID - 3
.Ipratropium (Atrovent) has been shown to provide relief only for excessive rhinorrhea
Advantages include that it does not cross the blood-brain barrier and is not
.systemically absorbed
: Adult
Perennial Allergic/allergic Rhinitis
Nasal spray (0.03%): 2 sprays (21 mcg/spray) per nostril q8-12hr; not to exceed 168-252
mcg/day
Seasonal allergic rhinitis: 2 sprays (0.06%) per nostril q6hr
:Pediatric
Allergic/allergic rhinitis
years: Safety & efficacy not established 6<
years: 2 sprays (0.03%) per nostril q6hr 6>
DECONGESTANTS - 5
Oral and topical decongestants improve the B-Phenylephrine (Neo- Synephrine) spray
nasal congestion associated with allergic or drops
rhinitis by acting on adrenergic receptors, i. Adults and children 12 years and
which causes vasoconstriction in the nasal older: 2 to 3 drops or one to two sprays in
mucosa, resulting in decreased each nostril, or small amount of jelly
inflammation. applied to nasal mucosa, every 4 hours as
A-Oxymetazoline hydrochloride (Afrin) spray or
drops needed. Do not use for more than 3 to
.5 days
i. Adults and children 6 years and older: 2 to 3
drops or sprays of 0.05% solution in each nostril ii. Children 6 to 12 years: 2 to 3 drops or
twice daily one to two sprays of 0.25% solution in
ii. Children 2 to 6 years: 2 to 3 drops of 0.025% each nostril every 4 hours as needed. Do
solution in each nostril twice daily .not use for more than 3 to 5 days
iii. Children younger than 6 years: 2 to 3
Use no longer than 3 to 5 days.
Discontinuing these drugs afterdrops
5 daysof 0.125%
may result solution
in a every 4 hours in
.each nostril as needed
Saline spray a. Saline spray is effective in-4
liquefying thick secretions and helps keep
. mucosa moist
Polypectomy
Reduction surgery of inferior turbinate
FOLLOW UP:
NSAID
Beta blockers
ACEI
Oral contraceptives
R H I N I T I S ME D I C A M E N TOS A