TARGET OBAT

Pustaka:
Abraham, D.J., (Ed.), 2003, Burger’s Medicinal Chemistry and Drug
Discovery, Sixth Edition, Vol. 1, John Wiley & Sons, Inc., New
York.
Foye, W.O., Lemke, T.L., & Williams, D.A., 2009, Principles of
Medicinal Chemistry, 5th Ed., Lea & Febiger, Boston.
Mutschler, E., 1999, Dinamika Obat, Edisi V, Penerbit ITB,
Bandung.
Siswandono, Soekardjo, B., (Ed.), 2000, Kimia Medisinal, Airlangga
University Press, Surabaya.
Thomas, G., 2007, Medicinal Chemistry, Second Edition, John Wiley
& Sons, Inc.,
New York.
Wilson, C.O., Gisvolds, O., & Doorge, R.F. (Ed.), 2011, Textbook of
Organic Medicinal and Pharmaceutical Chemistry, 12th Ed.,
Lippincott Co., Toronto.
 Farmakologi Molekuler

Penggunaan

Mekanisme molekuler

Obat Efek
Level aksi obat :
Tingkatan utama aksi obat dari yang sederhana menuju komplek :
- molekuler
- sub selluler
- sel
- organ atau jaringan
- organisme utuh
Molekul aksi obat :
- Molekul pembawa signal (ligand)/first messenger
- Reseptor
- Second messenger
- Intrasellular signal
- Protein target
- Respon