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PERIOPERATIVE:
AN INTRODUCTION
TIM PERIOPERATIF
DEPARTEMEN OBSTETRI-GINEKOLOGI
FAKULTAS KEDOKTERAN UNIVERSITAS INDONESIA
2014
Basic T1 T2 T3 T4
T1A T1B T2A T2B T3A T3B T4A T4B
Laboratory results:
Hb:6 Ht:18 L:15,000 Tr:70,000
pT:1.5xC, aPTT 2.5xC, Fib:150
D-dimer:1500
RBG: 180
Blood group: O+
Ureum: 80, Creatinine: 1.5
Albumin 2.8
UL: protein +2
Perioperative
Basic knowledge
Anatomy Physiology Pathology
PROBLEMS WHICH MAY OCCUR DURING
PERIOPERATIVE PERIOD
Brain ?
Respiration ?
Cardiovascular ?
Liver ?
Kidneys ?
Pancreas ?
Haemostasis ?
Nutrition ?
Immunology ?
OXYGEN DELIVERY
Airway
Breathing Oxygenation P aO 2
CaO2
Hemoglobin Carrying capacity S aO 2 DO2
PRELOAD AFTERLOAD
AEROBIC METABOLISM
O2
Glu O2
SYOK
Blood volume
Depends on weight and age
Coagulation (intrinsic pathway) Coagulation (extrinsic pathway)
Factor XI
TF
endothelium
Thrombogenic
Factor VIII Factor IX TM
Factor V Factor X
Prothrombin Thrombin
TF = Tissue Factor
TM = Thrombomodulin
Fibrinogen FIBRIN- TFPI = Tissue Factor Pathway Inhibitor
PLATELET
Protein S THROMBI Plasmin Plasminogen
A Protein C Protein C
a22PI
TM
Thromboresistant
TF tPA
endothelium
endothelium
Activated
PAI-1