FUNGAL

ENDOCARDITIS
FOR MY WIFE
INTRODUCTION

RARE PRESENTATION ASSOCIATED MULTIPLE ASPERGILLUS INCIDENCE EXPECTED TO

MORBDITIES ENDOCARDITIS IS MOST INCREASE DUE TO
SEVERE FORM INCREASED FREQUENCY OF
INVASIVE PROCEDURES.
POINTS TO NOTE

LACKS MOST CLINICAL FEVER ABSENT BLOOD CULTURE DIAGNOSIS LATE OR THESE FACTORS LEAD TO
CRITERIA (EG JONES NEGATIVE POSTMORTEM INCORRECT
CRITERIA) USED TO MANAGEMENT
DIAGNOSE INFECTIVE
ENDOCARDITIS
TREATMENT
TREATMENT

MOST PATIENTS REQUIRE SURGERY PATIENTS HAVE TO TAKE ANTIFUNGAL THE HIGH COST OF EICHONACANDINS
(>90%) AS COMPARED TO BACTERIAL TREATMENT LIFELONG AFTER THE HAVE LIMITED THEIR USE.
ENDOCARDITIS (45%) SURGERY
DRUG OF CHOICE - VORICONAZOLE
 FUNGAL ENDOCARDITIS HAS HIGH MORTALITY RATE

DELAYED/MISTAKEN DIAGNOSIS IS THE MAIN REASON

ACUTE LIMB ISCHAEMIA IS SIGNIFICANTLY HIGHER IN PATIENTS

HAVING FUNGAL ENDOCARDITIS
DISCUSSION
HEALTH CARE ASSOCIATED ENDOCARDITIS AND PROSTHETIC VALVE
ENDOCARDITIS ARE THE ONLY SIGNIFCANT RISK FACTOR
ASSOCIATED WITH ASPERGILLUS ENDOCARDITIS

ABSENCE OF FEVER AND AORTIC ABSCESS/PSEUDOANEURYSM

WERE ASLO FOUND TO BE ASSOCIATED.

ASPERGILLUS GALACTOMANNAN ANTIGEN CAN BE USED TO

DIAGNOSE ASPERGILLUS ENDOCARDITIS