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Mathematical Model for

Erythropoiesis
Saeed Khamis
2018003959
Introduction

To Model the process of Erythropoiesis


Motivation for the model
Erythrocytes

Erythropoiesis
Assumptions

The assumptions made for the preferred application by the


researchers consider the participants, so that it results in decreased
complexity of the model:

1. Healthy adult subject


2.Existence of a steady state
3. Enough iron concentration
4. Reasonable blood loss
Application
Patients suffering from Polycythemia vera (PV)

Effective for Clinical Decisions


Extending the Mathematical models in general
https://youtu.be/tHT4TlOyJWA?t=115
Conclusion
References
Fonseca, Luis L., and Eberhard O. Voit. “Comparison of Mathematical Frameworks for Modeling
Erythropoiesis in the Context

of Malaria Infection.” Mathematical Biosciences, vol. 270, 2015, pp. 224–236.,


doi:10.1016/j.mbs.2015.08.020

Fuertinger, Doris H., et al. “Prediction of Hemoglobin Levels in Individual Hemodialysis Patients by Means
of a Mathematical

Model of Erythropoiesis.” Plos One, vol. 13, no. 4, 2018, doi:10.1371/journal.pone.0195918.

Tetschke, Manuel, et al. “Mathematical Modeling of RBC Count Dynamics after Blood Loss.” Processes, vol.
6, no. 9, 2018, p.

157., doi:10.3390/pr6090157.

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