Features of Chromaster

Outstanding performance
Easy to use
Expandability

Fulfilling the customer’s needs.

“Chromaster” is a coined word combining Chromatograph
and Master. It represents Hitachi’s vision of developing
and providing a liquid chromatograph system that can
make valuable contributions as a powerful tool for a
skilled, “master” chromatographer.

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Outstanding performance
Two performance capabilities supporting data reliability

 the excellent reproducibility made possible by the pump and

autosampler

the excellent stability of the column oven and detector.

 Outstanding performance

DAD
- Low noise and drift
- High resolution
Column Oven
- Wide temperature range
UV/UV-VIS Detector
2-wavelength detection

Autosampler
- Good reproducibility
- Low carry-over
Detectors
Const-temperature cell *1

Pump
- Good flow rate precision
- Improved LP-gradient *1

*1: Optional units available

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Outstanding performance /Improved LP-Gradient

5110 Pump
Improved gradient performance and the
excellent flow rate precision
➣The Chromaster has a new low-pressure mode called
High Frequent Mode(HFM)
➣HFM delivers excellent gradient and retention time
reproducibility without the use of mixers at 800 μL
system delay volume.
High Frequent Mode (HFM) increases the switching frequency of the
proportioning valve for improvement in the mixing capacity of the mobile phase.

Drawing interval HFM schematics

A B A B
 Outstanding performance (Low carry-over) 　

Removal of dead volume, and active wash of needle outer wall by dedicated pump
provides extremely low carry-over. （ Spec.≦0.003 ％）

【 Needle connection structure 】 【 Injection port structure 】

Flared fitting
（ without a
ferule ） Needle
Gold solder
Seal
Flange needle 5 4

6 3

1 2
Injection valve
Pump Column

✓Removal of dead volume from needle Connection by means of a flange needle

(without a ferrule).
✓Removal of dead volume through the direct connection between the injection port
　 and the injection valve.
 Outstanding performance (2-wavelength detection)
1 0 0 . 0 0
9 0 . 0 0
8 0 . 0 0
7 0 . 0 0
U

6 0 . 0 0
A

5 0 . 0 0
4 0 . 0 0
m

3 0 . 0 0
2 0 . 0 0
1 0 . 0 0
0 . 0 0
0 . 0 0 1 . 0 0 2 . 0 0 3 . 0 0 4 . 0 0 5 . 0 0 6 . 0 0 7 . 0 0 8 . 0 0 9 . 0 0 1 0 . 0 0
分
1 0 0 . 0 0
9 0 . 0 0
8 0 . 0 0
7 0 . 0 0
U

6 0 . 0 0
A

5 0 . 0 0
4 0 . 0 0
m

3 0 . 0 0
2 0 . 0 0
1 0 . 0 0
0 . 0 0
0 . 0 0 1 . 0 0 2 . 0 0 3 . 0 0 4 . 0 0 5 . 0 0 6 . 0 0 7 . 0 0 8 . 0 0 9 . 0 0 1 0 . 0 0
分

ユ ー ザ ー 名 ： 　 S y s t e m プ ロ ジ ェ ク ト 名 ： 　 w _ W L _ 1 0 1 0 1 4
レ ポ ー ト メ ソ ッ ド 名 ： 　 カ タ ロ グ 用 1 0 _ 1 7 _ 2 印 刷 日 ： 　
レ ポ ー ト メ ソ ッ ドI D ： 　 1 2 0 2 2 0 1 0 / 1 0 / 1 4
ペ ー ジ 番 号 ： 　 1 / 1 1 5 : 2 5 : 4 8 A s ia / T o k y o

Sample: Pain
reliever
Aspirin
270nm
Unknown
component 205nm

salicylic acid

min
Data acquisition interval: 400 ms

Measurement wavelength of aspirin in Japan and the U.S. Pharmacopeia has been described as 270nm. However,
small peaks, such as aspirin degradation product of salicylic acid and an additive are difficult to detect in the
270nm wavelength.
However, by simultaneously setting the 270nm and 205nm wavelength, salicylic acid and additives can be
detected and measured.
 Easy to use

Column Oven Organizer

- Improved column capacity - improved bottle capacity
- Column management system *1

Autosampler DAD
- Thermostat rack *2 - Shorten stabilizing time
-
Dedicated degassing unit *1

Pump GUI Controller

- Auto-purge valve *
2
- Setting condition and control
- Plunger washing system all system modules
- Low volume degassing unit *1 - Color LCD
- Touch panel operation
*1: Optional units available
*2: Pre-installed model available

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 Easy to use

Column management system (option)

TAG
Storage the column information
Column connector
Generally useable for 3rd party columns

On CDS operation, the information (injection counts,

etc.) are stored in Tag automatically.
The information in the tag
can be read and edited
using the dedicated software.
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 Easy to use

GUI controller for central operation of the system (Option)

Monitor Main Menu

- Monitoring data and module status. - Operate the modules

- Display chromatogram (except
DAD) and pressure profile.

Setup Configuration
Setting measuring parameters Maintenance Configure the system
and sample parameters

Running
Conditioning
Wake up & Sleep

- Module calibration
- GLP function
- Setting the measuring condition
and starting single or series run
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 Easy to use

GUI manages automatic Wake up and Sleep procedure

Wake up : Performing the programmed pre- analysis procedure
by specified time.
(Automated system stabilization for series analysis start)

Sleep : Performing the programmed post-analysis procedure

from specified time or after series run.
　 (Saving solvent consumption, saving lamp life time, improve safety,
etc.)
Example of the parameters
Pump flow On/Off, Oven control On/Off,
Detector lump On/Off, Pump purge,
Autosampler syringe purge, etc.

The procedure is programmable as

multi-line time table.
　　 ex. Pump flow stop after Column
oven cooling down.

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 For Chromaster System Manager
- Up to 2 HPLC systems with One PC

* OpenLab can be up to 4 systems per PC

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Chromaster System
1. Fully automated Low Pressure GradientConfigurations
HPLC System

P/N Description Quantity

NST-892-0103 Chromaster 5110 Pump 1
NST-892-0151 Low-pressure Gradient Unit for 5110 1
NST-892-0156 6-channel Degassing unit 1
NST-892-0161 Plunger washing pump 1
NST-892-0203 Chromaster 5210 Autosampler 1
Chromaster 5310 Column Oven (220V)
NST-892-0305 e-Line cable (0.5m). Power unit is built-in. 30cm column x 1
3pcs can be loaded.
Chromaster Organizer (220V)
NST-892-0805 1
Power supply function for Pump, AS, IFC Board, Detector.
Chromaster 5410 UV Detector
NST-892-0403 With Flow Cell(path: 10mm, vol.: 13ul) e-Line cable (0.5m). 1
Organizer or AC Adaptor (150W) is required.
NST-892-0900 USB IF board 1
NST-892-0080 Chromaster System Manager (English) 1

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Chromaster System
2. Low Pressure Gradient Configurations
HPLC System with Manual Injector

P/N Description Quantity

NST-892-0103 Chromaster 5110 Pump 1
NST-892-0151 Low-pressure Gradient Unit for 5110 1
NST-892-0156 6-channel Degassing unit 1
Chromaster 5310 Column Oven (220V)
NST-892-0305 e-Line cable (0.5m). Power unit is built-in. 30cm column x 1
3pcs can be loaded.
Chromaster Organizer (220V)
NST-892-0805 1
Power supply function for Pump, AS, IFC Board, Detector.
Chromaster 5410 UV Detector
NST-892-0403 With Flow Cell(path: 10mm, vol.: 13ul) e-Line cable (0.5m). 1
Organizer or AC Adaptor (150W) is required.
NST-892-0080 Chromaster System Manager (English) 1
Interface box (S), I/F box, IFCB. USB-AID x 2 can be
NST-892-0963 mounted(option). AC Adaptor (60W) is required. 1
RHE-7725I Manual injector, 2/6,MAN,SYR,SS,W/Pos Sensor
Manual Injector Holder, Holder panel for 5110 Pump.Injector is
NST-892-0178 not included.
ALLHK-7725xxx Sample loop
ALLHK-80xxx Injector syringe

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Chromaster System
3. Low Pressure Gradient Configurations
HPLC System with two detectors

P/N Description Quantity

NST-892-0103 Chromaster 5110 Pump 1
NST-892-0151 Low-pressure Gradient Unit for 5110 1
NST-892-0156 6-channel Degassing unit 1
NST-892-0161 Plunger washing pump 1
NST-892-0203 Chromaster 5210 Autosampler 1
Chromaster 5310 Column Oven (220V)
NST-892-0305 e-Line cable (0.5m). Power unit is built-in. 30cm column x 1
3pcs can be loaded.
Chromaster Organizer (220V)
NST-892-0805 1
Power supply function for Pump, AS, IFC Board, Detector.
Chromaster 5410 UV Detector
NST-892-0403 With Flow Cell(path: 10mm, vol.: 13ul) e-Line cable (0.5m). 1
Organizer or AC Adaptor (150W) is required.
Chromaster 5440 FL Detector (220V)
NST-892-0465 e-Line cable (0.8m), Power unit and Flow Cell for 5440 (Volume 1
12uL, P/N: 892-0560) are equipped.
NST-892-0900 USB IF board 1
NST-892-0080 Chromaster System Manager (English) 1

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3. Two Row Alignment of Low Pressure Gradient HPLC System
with Two Detectors

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EXISTING COSTUMER
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