Prostate Cancer & Ultra

Natural Prostate
Prostate Cancer - Statistics

 4th most common cancer diagnosed in Malaysian man.

 45age above are at highest risk.
 Malaysian Male population aged 40-75 – 5,447 930.
 Annual mortality rate per 100,000 people
 2005 - 2.8
 2010 - 3.5
 2013 - 3.8
 2017 - 4.5

www.indexmudi.com
As at July 2017
Prostate Cancer - Statistics

 Prostate Awareness Campaign in 2005 at 12 district hospitals

 2770 participants.
 10% had PSA > 4ng/mL
 Malay highest PSA > 2.32ng/mL
 Indian lowest PSA > 1.3 ng/mL
 408 participants called for Biopsy, only 183 agreed for biopsy.
 30 PC detected.

Prostate cancer screening perspective, Malaysia

Sothilingam et al.2010.
Prostate Cancer

 The prostate gland is part of the male reproductive system.

 Prostate cancer is the most common cancer in men.
 It is treatable if diagnosed early, before it spreads.
 If symptoms appear, they include problems with urination.
 Regular screening Is the best way to detect it in good time.
Early stage prostate cancer

 Radical prostatectomy: The prostate is surgically removed.

 Brachytherapy: Radioactive seeds are implanted into the
prostate to deliver targeted radiation treatment.
 Conformal radiation therapy: Radiation beams are shaped so
that the region where they overlap is as close to the same
shape as the organ or region that requires treatment. This
minimizes healthy tissue exposure to radiation.
 Intensity modulated radiation therapy: Beams with variable
intensity are used. This is an advanced form of conformal
radiation therapy.
Advanced prostate cancer

 Advanced cancer is more aggressive and will have spread further

throughout the body.
 Chemotherapy may be recommended, as it can kill cancer cells
around the body.
 Androgen deprivation therapy (ADT), or androgen suppression
therapy, is a hormone treatment that reduces the effect of
androgen.
 The patient will likely need long-term hormone therapy.

 Radical prostatectomy is not currently an option for advanced cases,

as it does not treat the cancer that has spread to other parts of the
body.
What causes prostate cancer?

 The prostate is a exocrine gland. This means that its fluids and secretions are
intended for use outside of the body.
 The prostate produces the fluid that nourishes and transports sperm on their
journey to fuse with a female ovum, or egg, and produce human life. The prostate
contracts and forces these fluids out during orgasm.
 The protein excreted by the prostate, prostate-specific antigen (PSA), helps semen
retain its liquid state. An excess of this protein in the blood is one of the first signs
of prostate cancer.
 The urethra is tube through which sperm and urine exit the body. It also passes
through the prostate.
 As such, the prostate is also responsible for urine control. It can tighten and
restrict the flow of urine through the urethra using thousands of tiny muscle fibers.
Risk factors

 Among the many possible risk factors:

 Age
 Prostate cancer is rare among men under the age of 45 years, but more common after the
age of 50 years.

 Geography
 Prostate cancer occurs most frequently in North America, North-western Europe, on the
Caribbean islands, and in Australia.

 Genetic factors
 Certain genetic and ethnic groups have an increased risk of prostate cancer.
 In the U.S., prostate cancer is at least 60 percent more common and 2 to 3 times more
deadly among black men than non-Hispanic white men.
Risk factors

 A man also has a much higher risk of developing cancer if his identical twin has it,
 Man whose brother or father had prostate cancer has twice the risk of developing it
compared to other men.
 Diet
 Studies have suggested that a diet high in red meat or high-fat dairy products may
increase a person's chances of developing prostate cancer.
 Obesity
 Some studies have found that obesity increases the risk of death in advanced
cancers. Studies have also concluded that obesity decreases the risk that a cancer
will be low-grade if it does occur.
Ultra Natural Prostate

Benefits at a Glance:
 Supports prostate health with cutting-edge nutrients
 Helps protect against excess estrogen levels
 Promotes healthy prostate size and structure
 Inhibits undesirable cell division changes
 Supports healthy urinary patterns and flow
 Encourages a healthy inflammatory response
Promotes healthy prostate size and
cell structure
 Lycopene is an antioxidant carotenoid and potent prostate health nutrient
because it promotes healthy prostate size and structure.
 Boron has been shown to slow the elevation of prostate-specific antigen.
 AprèsFlex® is an ultra-absorbable extract of Boswellia that supports normal
inhibition of 5-lipoxygenase, an enzyme that is associated with undesirable
cell division changes.
Supports healthy urination & inflammation response

 Graminex® Flower Pollen Extract™ relaxes the smooth muscles of the urethra
and helps regulate inflammatory reactions.
 Saw Palmetto CO2 extract supports normal urinary flow and promotes a
healthy inflammatory response as well.
 Pygeum extract also supports healthy urination patterns. beta-sitosterol (in
pygeum) enhances pygeum's effects.
 This formula contains additional beta-sitosterol (from pine) as well as
pumpkin seed CO2 oil to complement the active compounds of both saw
palmetto and pygeum plant extracts.
Encourages healthy estrogen levels

 As men age, testosterone often converts to estrogen at higher rates.

But prostate cells are very sensitive to estrogen's effects.
 Standardized lignans from flax seed and Norway spruce knotwood
convert to enterolactone in the body. Enterolactone helps support
vulnerable prostate cells against the effects of excess estrogen levels.
 Stinging and Dwarf nettle root extracts help support prostate cells
against excess estrogen levels.
ZINC
 zinc may have a protective effect against injury to the prostate
induced by cadmium.
 Studies have shown that cadmium can induce prostate tumors in
rats, and the element has been found in greater concentrations
in cancerous prostate tissue than in normal tissue.
 Cadmium’s mechanism in the development of prostate cancer is
likely to involve genotoxic effects, such as those resulting in
reduced DNA repair and greater activation of genes associated
with cell proliferation.
 Zinc stimulates the availability of proteins called
metallothioneins which increase cadmium binding, resulting in
its removal from circulation and a reduction of its adverse
effects.
SELENIUM & VITAMIN E

 Low plasma selenium is associated with a four- to fivefold

increased risk of PC.
 levels of plasma selenium also decrease with age, resulting in
middle-aged to older men being at a higher risk for low
selenium levels.
 A large-scale study of almost 11,000 men in Maryland showed
that the protective effects of high selenium levels, and
similarly that of the alpha-tocopherol isomer of vitamin E,
were only observed when the concentrations of the gamma
tocopherol isomer of vitamin E were also high.
VITAMIN D3

 A study published in 2012 evaluated a group of men with early-

stage prostate cancer who received a 4,000 IU vitamin D3
supplement each day for a year (Marshall 2012).
 After one year, 55% of the men showed a decrease in tumor-
sensitive biopsies. An additional 11% showed no change (meaning
the cancer had not progressed).
 Only 34% of men taking vitamin D progressed compared to 63% of
the control group. This repre­sents a 46% reduction in the number
of men who moved to advancing disease, indicating powerful
effects of taking 4,000 IU/day of vitamin D for one year.
References

 https://prostate.net/articles/how-japanese-men-prevent-prostate-cancer
 
 http://www.prostatereport.com/reviews/life-extension-ultra-natural-prostat
e.php
 
 http://homeremedies9.com/common-remedies/home-remedies-p/prostate-di
sorders-home-remedies/
 
 https://www.sciencedirect.com/science/article/pii/S2214388215000235
 
 http://global-disease-burden.healthgrove.com/l/34146/Prostate-Cancer-in-M
alaysia