Systems Biology:

The Next Frontier for

Bioinformatics
 Main Textbook

Systems Biology:
Constraint-based
Reconstruction and
Analysis,

1st Edition

Bernhard O. Palsson, 2015

3
 Life: An Introduction to
Complex Systems Biology,

1st Edition

K. Kaneko, 2006

4
 Systems Biology: Integrative
Biology and Simulation Tools

Editors:
A. Prokop & B. Csukás , 2013

5
 Outline
 Preface
 Introduction to Mathematical Modeling and Simulation
 Systems Biology
 Complex (Biological) Networks
 Computational Tools and Resources for Integrative Modeling in Systems
Biology
 GENRE (GENome-scale Reconstructions)
 Genome-scale Metabolic Network Reconstructions
 COBRA (COnstraint-Based Reconstruction and Analysis)
 Concluding Remarks
6