This document summarizes renal and pulmonary scintigraphy procedures. For renal scintigraphy, it discusses using Tc-99m DTPA to evaluate glomerular filtration rate and renal function by examining renal blood flow, accumulation time, and excretion time on a renogram. For pulmonary scintigraphy, it discusses using perfusion scans with agents like Tc-99m MAA and ventilation scans with radioactive gases or radioaerosols like Xenon-133 to detect defects. It provides an example of a 75 year old woman where the ventilation scan was normal but the perfusion scan revealed multiple large segmental defects in both lungs.
This document summarizes renal and pulmonary scintigraphy procedures. For renal scintigraphy, it discusses using Tc-99m DTPA to evaluate glomerular filtration rate and renal function by examining renal blood flow, accumulation time, and excretion time on a renogram. For pulmonary scintigraphy, it discusses using perfusion scans with agents like Tc-99m MAA and ventilation scans with radioactive gases or radioaerosols like Xenon-133 to detect defects. It provides an example of a 75 year old woman where the ventilation scan was normal but the perfusion scan revealed multiple large segmental defects in both lungs.
This document summarizes renal and pulmonary scintigraphy procedures. For renal scintigraphy, it discusses using Tc-99m DTPA to evaluate glomerular filtration rate and renal function by examining renal blood flow, accumulation time, and excretion time on a renogram. For pulmonary scintigraphy, it discusses using perfusion scans with agents like Tc-99m MAA and ventilation scans with radioactive gases or radioaerosols like Xenon-133 to detect defects. It provides an example of a 75 year old woman where the ventilation scan was normal but the perfusion scan revealed multiple large segmental defects in both lungs.
• Renogram • Parenkim ginjal Radiopharmaceutical : Tc-99m DTPA Radiopharmaceutical : Tc-99m DTPA • Excreted by glomerular filtration GFR GFR • Excreted by glomerular filtration • No • Notubular reabsorption tubular reabsorption • Not • Notmetabolized metabolized • Split • Splitfunction function Normal renogram
Three phases in renogram :
1. The initial : • sharp rise which was attributed to the renal blood flow 2. Accumulation (secretion) • A slower rise • Time to peak : 2 – 4.5 min • Difference of the time to peak of both kidney is not more than 1 min. • The time to peak is affected by the urine flow rate 3. Excretion • A decline due to renal excretion of the compound, • depends on the outflow tract. • Time to half max: 4.75 – 11.5 min. • The time to half peak is longer in patients with impaired renal function Pulmonary scintigraphy
– Tc-99m MAA Radioactive gases Xenon-133 (macroagregatealbumine) Xenon-127 – Tc-99m microsphere Krypton-81m – Tc-99m human serum albumin Radioaerosol Tc-99m phytate Tc-99m DTPA Tc-99m sulfurcolloid Technegas 75 yrs old woman with 6 days of dyspnea The chest radiograph is normal
The xenon ventilation scan is normal,
while the perfusion scan reveals multiple defects in both lungs comprising large portions (complete in many) of multiple segments. Terima Kasih