Afterload, preload and pressure

Myocardial dysfunction

Myocardial failure

Heart, pump failure

Diastolic dysfunction failure Systolic dysfunction failure CO SV Compensatory neurohormonal

activation

ventricular diastolic perfusion of tissues in the body

pressure Easy Release of norepinephrine
fatigability and atrial natriuretic peptide
oxygen supply to tissues and body
peripheral capillary weakness
pressure CO
Myocardium: cardiac workload
Congestion
HR
blood flow to myocardium
Peripheral
Sinus tachycardia
Ischemia
Edema

Inaerobic metabolism

Increased lactic acid production

Chest pain