the thoughts, feelings, and behaviors of a person preventing them from leading a happy, healthful productive life. RISK FACTORS Abuse or neglect as a child Childhood problems with temperament Family or personal history of mental illness or substance abuse Intelligence below normal Low birth weight Lower socioeconomic status Parental absence or criminal activity Prenatal exposures, such as to alcohol or drugs Significant medical conditions, such as cancer, chronic pain, and hypothyroidism Social disadvantage Stressful or Traumatic life events Substance abuse