Morning Report

Hadeel AL Dherat M. D
Brief history

 28 year old female patient with sudden onset of KFT deterioration.

 Has pleural effusion, ascites
 Blood pressure 140/80
Gross

 Three needle cores longest measuring 0.7 cm shortest measuring 0.3 cm.
PAS
Masson trichrome
Microscopic features

 1. Adequate kidney biopsy

 2. Glomerulin show increased mesangial Cellularity, leukocytic cell infiltrate
mainly neutrophils,proliferation and swollen intercapillary
 3. Tubules some showing thyroidizatiin
 4. Interstitial lymphocytic cell infiltrate
 5. Blood vessels are unremarkable
Differential diagnosis

 Active VS Chronic
 Whats the main part that is involved?
 What about other parts of the nephrone?
Glomerulonephritis
What type?
Proliferaive
Post infectious
Final diagnosis
Post infectious /post streptococcal proliferaive glomerulonephritis / exudative
type.
How to approach kidney biopsy
Reading and reporting
 1. Determine adequacy?
 renal biopsy must contain glomeruli to be considered adequate,
 a good guideline to follow is that at least 5–10 glomeruli should be examined
to properly assess the extent of the disease.
 2. List the parts of the nephrone and comment on each
Glomerular comments

 1. Mesangial hypercellularity? 4or more nuclei between capillaries

 2.
Thank you for your attention