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8 - Farmakologi Obat Penyakit Tulang Dan Sendi - NEW
8 - Farmakologi Obat Penyakit Tulang Dan Sendi - NEW
• The goal of urate-lowering therapy is to achieve and maintain serum uric acid less
than 6 mg/dL (357 μmol/L), and preferably less than 5 mg/dL (297 μmol/L) if
signs and symptoms of gout persist.
• Intra-articular (IA) corticosteroid injections are recommended for both hip and
knee OA when analgesia with acetaminophen or NSAIDs is suboptimal. Injections
can be given with concomitant oral analgesics for additional pain control. Do not
administer injections more frequently than once every 3 months to minimize
systemic adverse effects.
• Concomitant folic acid may reduce some adverse effects without loss of efficacy.