Biliary atresia is a progressive inflammatory process that causes fibrosis of the intrahepatic and extrahepatic bile ducts, eventually leading to ductal obstruction. It presents with jaundice, lighter stools, dark urine, hepatomegaly, poor weight gain, and irritability in infants. The exact cause is unknown but is thought to involve an immune reaction to a viral infection in susceptible infants. Diagnostic evaluation includes blood tests, imaging like ultrasound and hepatobiliary scintigraphy, and potentially liver biopsy. Treatment involves bile drainage procedures, antibiotics, nutritional support including fat-soluble vitamins, and nursing management focused on family support and education.
Biliary atresia is a progressive inflammatory process that causes fibrosis of the intrahepatic and extrahepatic bile ducts, eventually leading to ductal obstruction. It presents with jaundice, lighter stools, dark urine, hepatomegaly, poor weight gain, and irritability in infants. The exact cause is unknown but is thought to involve an immune reaction to a viral infection in susceptible infants. Diagnostic evaluation includes blood tests, imaging like ultrasound and hepatobiliary scintigraphy, and potentially liver biopsy. Treatment involves bile drainage procedures, antibiotics, nutritional support including fat-soluble vitamins, and nursing management focused on family support and education.
Biliary atresia is a progressive inflammatory process that causes fibrosis of the intrahepatic and extrahepatic bile ducts, eventually leading to ductal obstruction. It presents with jaundice, lighter stools, dark urine, hepatomegaly, poor weight gain, and irritability in infants. The exact cause is unknown but is thought to involve an immune reaction to a viral infection in susceptible infants. Diagnostic evaluation includes blood tests, imaging like ultrasound and hepatobiliary scintigraphy, and potentially liver biopsy. Treatment involves bile drainage procedures, antibiotics, nutritional support including fat-soluble vitamins, and nursing management focused on family support and education.
Presented to:Madam zara BILIARY ATRESIA • Definition Is a progressive inflammatory process that cause both intrahepatic and extrahepatic bile duct fibrosis, resulting in eventual ductal obstruction. ETIOLOGY • the exact cause of BA is unknown, although • Immune mechanism of viral injury. • Viral Infection in Susceptible Infants. CLINICAL MANIFESTATIONS 1. Jaundice 2. Dark yellow urine 3. Stools lighter 4. Hepatomegaly 5. Abdominal distention 6. Poor weight gain 7. Growth failure 8. Pruritus 9. Irritability DIAGNOSTIC EVALUATION BLOOD TESTS: • cbc • Electrolytes • Bilirubin • Liver enzymes LABORATORY ANALYSIS • Alpha1 antitrypsin Level • TORCH titers • Hepatitis serology • Urine CMV • Abdominal ultrasonography • Hepatobiliary scintigraphy • Endoscopic retrograde cholangiopancreatography • Percutaneous liver biopsy THERAPEUTIC MANAGEMENT • Bile drainage • Prophylactic antibiotics • Nutritional support • Medium-chain triglycerides • Essential fatty acids • Supplement with fat soluble vitamins(A D E K) • Multivitamins and minerals NURSING MANAGEMENT • support of family before during and after surgical p procedure • Education regarding treatment plan • Teaching include the proper administration of medi cation • Administration of nutritional therapy • Psychology support