Prinsip Farmakoterapi Rasional

Alfi Yasmina
DPK – 14 Februari 2020
Penggunaan antibiotik pada infeksi saluran
nafas atas karena virus
Peresepan antibiotik lini kedua atau ketiga
yang lebih mahal sebelum memulai dengan
antibiotik lini pertama tanpa alasan jelas
Tidak meresepkan oralit pada diare akut
Penggunaan injeksi intravena, padahal bisa
diberikan per oral
Rational use of medicines requires that "patients
receive medications appropriate to their clinical
needs, in doses that meet their own individual
requirements, for an adequate period of time,
and at the lowest cost to them and their
community".
WHO conference of experts, Nairobi 1985
Proses Peresepan Dokter
Mendefinisikan masalah pasien (diagnosis)
Mendefinisikan terapi yang efektif dan aman
(farmakologis dan non-farmakologis)
Memilih obat yang tepat, cara pemberian dan dosis yang
tepat, durasi yang tepat
Menulis resep yang rasional, benar, dan jelas
Memberi pasien informasi yang memadai (konseling)
Evaluasi respons terapi
Sumber referensi pemilihan obat

Clinical guidelines
National Essential Medicines List
Independent information on medicine
Non-independent information on medicine
Others
Clinical Guidelines
International/National Medical Societies
CV system: AHA, ESC
Diabetes: ADA, Perkeni
National Medical Authorities
NICE (UK)
Standard treatment in hospitals
PPK Pelayanan Medis
 National Essential Medicines List

WHO Model List of Essential Medicine – 2019

WHO Essential Medicines List for Children – 2019
National List of Essential Medicine/Daftar Obat Esensial
Nasional – 2013
Formularium Nasional – 2019
Independent information on medicine

International drug regulatory bodies:

FDA (US)
EMA (Europe)
MHRA (UK)
National drug regulatory bodies:
BPOM – IONI, PIO Nas
Non-dependent information on medicine

MIMS – Indonesia
DOI
 Others

High-quality studies in high-quality journals

Textbooks
Pharmacology - Applied
Disease-related