Utility and Interpretation of SARS-CoV-2

Serology
What Do We Know About SARS-CoV-2
Serology?
Overview of Diagnostic Tests
Composition of SARS-CoV-2
A Look at Antigens and Antibodies
What Do We Know About the Immune
Response to COVID-19?
IgM and IgG Responses in Symptomatic
Patients
Can We Combine Testing?
Combining RNA and Serology Tests
Improved Sensitivity of Diagnosis
What Does a Positive Serology Test for
SARS-CoV-2 Mean?
Systemic Review of Serological Testing
Cochrane Review of Antibody Tests
Is the COVID-19 Antibody Response
Pathogenic or Protective?
Significance of IgG Levels
Can Serology Testing Determine
Transmission Risk?
Is There a Practical Application for Serology
Testing of Healthcare Workers?
Use of Serology Tests as a Marker of
Exposure and for Surveillance
What About Use of Serology Testing in
Population-Based Surveys?
A Look at Asymptomatic Transmission Rates
Concluding Remarks
Abbreviations