Dieth with High Saturated

 Gender: Female Fats

 Early Menarche  Weight: 84 kg; BMI: 31.6

over expressed estrogen increase in fat tissues high level of insulin

increased estrogen level
receptor

estrogen levels
increased are rasied
estrogen
exposure

INCREASED ESTROGEN
METABOLISM

increased breast cell

proliferation

INITIATION PHASE:
Carcinogens bind to the cell’s DNA; results
to alteration of functions

Genotoxic waste in estrogen Sponatneous error in cell

metabolism duplication

Somatic mutations in the DNA