GREEN CHEMISTRY

T.Y. B.Sc.
 Principles of Green Chemistry
• 12 Principles of Green Chemistry
• Paul Anastas (coined term)
• Working Definition: “Green Chemistry
efficiently utilizes (preferably renewable) raw
materials, eliminates waste and avoids the use
of toxic and/or hazardous reagents and
solvents in the manufacture and application of
chemical products.”
Principles of Green Chemistry summed in a picture
 Principles of Green Chemistry
• Waste
  prevention instead of remediation.
• Atom Efficiency: Maximize the efficiency of
incorporation of atoms in the product.

• Compare the Atom economy of the following

reactions:
a) Diels Alder reaction of butadiene and ethene
b) Acetylation of aniline using acetic anhydride
c) Dehydrohalogenation of tert-butyl bromide
• Less hazardous/toxic chemicals
 Oxidation of organic compounds using
peroxides or molecular oxygen rather than use
of conventional Cr/Mn oxidizing agents (ex.)
• Safer products by design
• Innocous solvents and auxiliaries
 Water, supercritical CO2, Ionic liquids, deep
eutectic solvents
• Energy efficient by design
 Microwave, ultrasound rather than
conventional heating
• Preferably renewable raw materials
 Biomass, Methane, CO2, Glucose  Shikimic
acid  Adipic acid
• Shorter synthesis (avoid derivatisation)
• Catalytic rather than stoichiometric reagents
(ex.)
• Design products for degradation
• Analytical methodologies for prevention of
pollution
• Inherently safer processes
Think GREEN!!!