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  • Gastric Peptic Ulcer Disease

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    Amira FR
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    Gastric peptic ulcers are defects in the gastric mucosa that extend through the muscularis mucosa. They are caused by an imbalance between aggressive factors like H. pylori, NSAIDs, alcohol, acid, pepsin, and stress, and defensive factors like mucous, bicarbonate, prostaglandins, and epithelial renewal. Common symptoms include epigastric pain, nausea, chest discomfort, dyspepsia, and hematemesis.

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    Gastric peptic ulcers are defects in the gastric mucosa that extend through the muscularis mucosa. They are caused by an imbalance between aggressive factors like H. pylori, NSAIDs, alcohol, acid, pepsin, and stress, and defensive factors like mucous, bicarbonate, prostaglandins, and epithelial renewal. Common symptoms include epigastric pain, nausea, chest discomfort, dyspepsia, and hematemesis.

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    9 views7 pages

    Gastric Peptic Ulcer Disease

    Uploaded by

    Amira FR
    Gastric peptic ulcers are defects in the gastric mucosa that extend through the muscularis mucosa. They are caused by an imbalance between aggressive factors like H. pylori, NSAIDs, alcohol, acid, pepsin, and stress, and defensive factors like mucous, bicarbonate, prostaglandins, and epithelial renewal. Common symptoms include epigastric pain, nausea, chest discomfort, dyspepsia, and hematemesis.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
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    Gastric Peptic Ulcer Disease

    Definition
    • Gastric peptic ulcers are
    defects in the gastric
    mucosa that extend
    through the muscularis
    mucosa.
    Etiology

    Severe
    Lifestyle Genetic
    H. pylori Drugs physiologic
    factors factors
    stress
    Pathophysiology

    Imbalance between the aggressive factors and the


    defensive mechanisms
    Aggressive factors Defensive factors

    • NSAIDs
    • Helicobacter pylori • Mucous
    • Alcohol • Bicarbonate
    • Acid • Prostaglandins
    • Pepsin • Epithelial renewal
    • Stress
    • Smoking
    Symptoms

    Epigastrial Chest
    Nausea Dyspepsia
    pain discomfort

    Hematemesis

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