Professional Documents
Culture Documents
Urinary Tract Infection
Urinary Tract Infection
• Epidemiology
• Terminology
• Etiopathogenesis
• Microorganism
• Risk Factors
• Innate Host Response
• Clinical Features
• Acute Simple Cystitis
• Pyelonephritis
• Protatitis
• Diagnosis
• Treatment
• Complications
UTI
UTI is inflammation of urinary tract due to infectious agent,
comprises of variety of clinical entities, from subclinical infection
asymptomatic bacteriuria to disease like cystitis, prostatitis, and
pyelonephritis.
DIPSTICK
Detects the presence of leukocyte esterase and nitrite in the
urine. Leukocyte esterase corresponds to pyuria and nitrite
reflects the presence of Enterobacteriaceae, which convert
urinary nitrate to nitrite. Leukocyte esterase may be used to
detect >10 leukocytes per high power field (sensitivity of 75 to
96 percent; specificity of 94 to 98 percent) . A positive nitrite
test is a reliable index of significant bacteriuria, although a
negative test does not exclude bacteriuria.
URINE CULTURE
Acute Pyelonephritis
• Renal corticomedullary abscess
• Perinephric abscess
• Emphysematous pyelonephritis
• Papillary necrosis
• Xanthogranulomatous pyelonephritis
EMPHYSEMATOUS PYELONEPHRITIS
• Emphysematous pyelonephritis is a gas-producing,
necrotizing infection involving the renal parenchyma and, in
some cases, perirenal tissue.
• Diabetes mellitus and urinary tract obstruction are the major
risk factors.
• These infections are usually due to Escherichia coli or
Klebsiella pneumoniae , other causative organisms include
Proteus, Enterococcus, Pseudomonas, Clostridium, and, rarely,
Candida spp.
• Diagnosis by plain films of the abdomen and/or computed
tomography (CT). Such radiographs reveal air in the renal
parenchyma, bladder, or surrounding tissue in 50 to 85
percent of cases
• Clinical features are fevers, chills, flank or abdominal pain,
nausea, and vomiting.
• Treatment includes nephrectomy or open drainage along
with systemic antibiotics.
XANTHOGRANULOMATOUS PYELONEPHRITIS