Professional Documents
Culture Documents
Technique and
Practice
© Royal College of Obstetricians and Gynaecologists
MRCOG part 1 committee
It's not easy to write good
questions
Hb (g/dl)
• Ordinal
• Nominal
• Binary
• Interval
• Prunella
Technique
(The dodgy fifth option)
• Technique
If one of the stems is unknown to you it is probably fake (sometimes it’s
difficult to think of a fifth option
e.g.:
– Chi cubed distribution test
– Power is the unequal standard deviations compared to the means
– Turkie’s survival curves
• Knowledge
Stats know your scales!!
Knowledge
• All questions are derived from the blueprint
grid
Dear Candidate
If you have ten fingers and ten toes you will not
require a calculator
Formulae
• Sensitivity
•
• Power
Specificity
• + Predictive value • Understanding box plot
• - Predictive value
• Likelihood ratios
• Understanding histograms
• P values • Understanding forest plot
• Normal distribution
• Interquartile range • Which test to select
• Variance • Types of trial
• Standard deviation
• Standard error of the mean • ROC
• Mean, mode, median
•
• RR, OR, AR
Type I and type II error
• If TP=true positive and FN= false negative what
does the following equation represent
TP/(TP+FN)
• Select the best option.
• A Sensitivity
• B Specificity
• C Positive predictive value
• D Negative predictive value
• E Likelihood ratio
Technique
• Use pen and paper
DISEASE
+ -
TEST + TP FP
- FN TN
A population of 100 women after a gold standard test
(laparoscopy), 4 are found to have rectovaginal
endometriosis. A preoperative MRI has positive results for
rectovaginal endometriosis in 3 of the 4 true positives and
another 7 positives without rectovaginal endometriosis.
A 10 %
B 25 %
C 55 %
D 75 %
E 93 %
LAP + LAP -
MRI + 3 7
MRI - 1 89
4 96 100
LAP + LAP -
MRI + TRUE + FALSE +
MRI - FALSE - TRUE -
96 100
If P is set to <0.05 in a hypothesis testing trial there will be an alpha
error rate. Select the best option that reflects the average alpha error
rate with the defined P value.
A 1 in 25 trials
B 1 in 20 trials
C 1 in 10 trials
D 1 in 5 trials
E 1 in 3 trials
Answer
1 in 20 trials
Comments
The p value is the probability of an observation occurring by chance.
Alpha error is falsely rejecting the null hypothesis (no difference in the
two groups)
In a population of 110 women after a gold standard test
(laparoscopy), 10 are found to have rectovaginal endometriosis.
A preoperative endoanal scan has positive results for
rectovaginal endometriosis in 5 of the 10 true positives and
another 10 positives without rectovaginal endometriosis.
Choose the best option that reflects the specificity of the test.
A 50 %
B 60 %
C 70 %
D 80 %
E 90 %
LAP + LAP -
uss + 5 10
uss - 5 90
10 100 110
LAP + LAP -
uss + TRUE + FALSE +
uss - FALSE - TRUE -
100 110
A 10 %
B 20 %
C 30 %
D 40 %
E 50 %
LAP + LAP -
uss + 3 7
uss - 1 89
4 96 100
Answer
30 %
Comment
True test positives/ total test positives
• A new antihypertensive is assessed by a randomised controlled trial
in pregnant women. The main outcome is blood pressure four
weeks after treatment.
• What test would you use to compare the mean blood pressures in
the groups
A Linear regression
B Two sample T Test
C R squared co-efficient
D Regression analysis
E Chi Squared
A Sensitivity
B Specificity
C Positive likelihood ratio
D Negative likelihood ratio
E Positive predictive value
Answer A Sensitivity
• With regard to a box plot. What does the box
represent
A Bananas
B Beef
C Oily fish
D Soya milk
E Wheat
C Oily fish
Where is the body is the major production
of 1,25 (OH)2 D3 (calcitriol)
A Bone
B Kidneys
C Liver
D Lung
E Parathyroids
B Kidneys
With regard to bound plasma calcium, what is the major carrier
A Neutrophils
B Calciprotein transfer molecule 1 (CTM 1)
C Haemoglobin
D Plasma proteins
E SHBG
D Plasma proteins
What is the change in total lung capacity in pregnancy
A III, IV
B IX, X
C V, VII
D XI, XII
E XI, XIII
Correct answer:
E XI , XIII
Any comments or feedback:
Main changes in haemostasis factors during pregnancy.
Platelet count ↓
II, V =
Fibrinogen,VII,VIII,von Willebrand factor,IX,X,XII ↑
XI, XIII =↓
Antithrombin =
What factor shifts the O2 dissociation curve to the right (ie
reduces Hb affinity for 02)
E Reduced temperature
A Antrum
B Blastocyst
C Lacuna
D Basal lamina
E Uniblastocyst
A Antrum
Where is the body is calcidiol produced
A Kidneys
B Liver
C Parathyroids
D Skin
E Spleen
B Liver
What proportion of primordial follicles undergo atresia
to create a primary follicle
A 20 %
B 50 %
C 90 %
D 95 %
E 99%
E 99 %
• Don’t be scared of the stats question
• Good luck!!!