Professional Documents
Culture Documents
MANAGEMENT
Dr. Pawan Bhusal.
Introduction 4
I. PRIMARY HEADCHE
A headache that is not caused by another
underlying disease, trauma or medical condition.
Accounts for about ninety percent of all
headaches.
8
Most common-69%
Episodic or chronic
Primary disorder of CNS pain
modulation
seen equally in both sexes
13
Precipitating factors
Stress: usually occurs in the afternoon after long stressful
work hours or after an exam
Sleep deprivation
Uncomfortable stressful position and/or bad posture
Irregular meal time (hunger)
Eyestrain
Caffeine withdrawal
Dehydration
Symptoms & Signs 14
Pharmacological
Management
Chronic management
Emergency management
II- CLUSTER HEADACHE 38
Management
Non drug treatment
Preventive therapy
Abortive therapy
26
Management
Non drug treatment
Avoid headache triggers: foods, drugs,
activities
Avoid frequent abortive treatment
Stop smoking
Normalize sleeping and eating
Exercise
Relaxation and biofeedback
Psychotherapy
27
Management
Preventive Treatment
Tricyclic antidepressants (first-line)
o Amitriptyline
Beta-blockers (first-line)
o Atenolol, nadolol
Ca++ channel blockers – less effective
o Verapamil most commonly used
28
Management
Preventive Treatment
Anticonvulsants (second-line; valuable)
Valproate and topiramate are quite effective
Gabapentin
Lamotrigine, levetiracetam
Pregabalin
29
Management
Preventive Treatment
Ergots: Rarely used for prevention
o Side effects may be problematic
o Methylsergide: fibrosis (use 6 months
max)
MAOIs: Can be very effective
o Tyramine-free diet a must
o Numerous drug interactions
30
Management
Abortive Treatment
Simple and combined analgesics e.g NSAIDs.
Mixed analgesics (barbiturate plus simple
analgesics)
Ergot derivatives
Triptans
Opioids
31
Management
Triptans:
Serotonin 5-HT1 agonists
Reduce neurogenic inflammation
Most effective if used at onset of headache or aura, though
may be helpful at other phases
Used specifically for migraine
For nonresponders, try ergots (also act on NE, DA,
other receptors)
32
Management
Other Agents
Antiemetics/Neuroleptics:
o often combined with abortive agents
o Prochlorperazine, hydroxyzine, promethazine,
metoclopramide
III- Trigeminal Neuralgia 34
divisions of
and 3rd
Lancinating pain in 2nd
trigeminal nerve
>50yrs
Severe, brief ,repetitive pain causing patient to flinch
cold wind
Management
37
Carbamazepine
Intolerant-Gabapentin/Pregabalin
Injection of alcohol into peripheral branch of nerve
Posterior craniotomy to relieve vascular compression of
trigeminal nerve
44