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DEHYDRATION
Dehydration
whenever the total output of fluid exceeds the total
intake
Etiology:
insensible losses: through the skin , respiratory tract.
through increased renal excretion
through the GI tract
ketoacidosis and extensive burns.
Massive injury
Why infants are more susceptible to dehydration?
Water Balance in Infants
Extracellular > intracellular
approximately 60% of fluid is lost from the ECF
High insensible loss through skin
Body Surface Area
Kidney Function
The infant is less able to handle large quantities of solute-free
water than is the older child
How to calculate Daily Maintenance Fluid
Requirements??????????
TYPES OF DEHYDRATION
1. Isotonic (isosmotic or isonatremic) dehydration, the primary
form of dehydration
2. in children occurs in conditions which electrolytes and water
are lost in equal proportions , Na between 130 and 150
3. mEq/L.
.
2. Hypotonic (hyposmotic or hyponatremic) dehydration-Occurs
when the electrolyte deficit exceeds the water deficit
-Serum sodium levels are typically less than 130 mEq/L (clinical
example-near drown)
3. Hypertonic (hyperosmotic or hypernatremic)
dehydration water loss
in excess of electrolyte loss and is usually caused by a
proportionately larger loss of water or a larger intake of
electrolytes
Plasma sodium concentration is greater than 150 mEq/L
Involved organs:
1. Stomach+ intestine: (gastroenteritis)
2. Small intestine: (enteritis)
3. Colon: (colitis)
4. Colon+ intestine: (enterocolitis)
CLASSIFICATION OF DIARRHEA
Acute diarrhea:
upper respiratory/ urinary tract infections/ Antibiotic therapy/
laxative use
self-limited (< 14days duration)
Acute infectious diarrhea caused by viral, bacterial, and parasitic
Chronic diarrhea:
Parasite: Cryptosporidium
Why antibiotic administration increase cause diarrhea?
PATHOPHYSIOLOGY
Enteric pathogens-- affect
mucosal cells increase intestinal secretions toxins &
decreased intestinal absorption intestinal damage or
inflammationEnteric pathogens attach to the
mucosal cells diarrhea
symptoms such as the presence of fever, vomiting, frequency, and character of stools
Neutrophils or red blood cells in the stool indicate bacterial
gastroenteritis or inflammatory bowel disease
1. Hypothyroidism
2. Hyperparathyroidism
Others
1. Antacids
2. Diuretics
3. iron supplementation
4. Spinal cord lesion
NEWBORN PERIOD
Intestinal atresia or stenosis,
Hirschsprung disease (congenital aganglionic megacolon),
hypothyroidism,
meconium plugs,
meconium ileus
INFANCY
Hirschsprung disease, hypothyroidism, and strictures.
Constipation in infancy is often related to dietary practices.
less common in breast-fed infants
In case of constipation, increase the amount of cereal,
vegetables, and fruit
CHILDHOOD
A child who has experienced discomfort during bowel
movements may deliberately try to withhold stool.
in school-age: stresses and changes in toileting patterns.
Treatment in this case: