 Povidone is a synthetic polymer consisting of

linear 1-Vinyl-2-pyrroldionone groups.

 The degree of polymerization results in materials
of various molecular weight range.
 Povidone is usually available in four viscosity
grades identified by their K values, which
approximate K-15, K-30, K-60 and K-90.
 The average molecular weight of these grades are
10,000 40,000, 160,000 and 360,000 respectively.
 The most common uses of Povidone in
pharmaceuticals (frequently K-30) are as a tablet
binder and a tablet coating.
 A series of acrylate polymer is marketed under
Eudragit. Eudragit is trademark of Rohm GmbH
& Co. KG. Darmstadt in Germany, first marketed
in 1950s.
 Eudragit is prepared by the polymerization of
acrylic and methacrylic acids or their esters, e.g.,
butyl ester or dimethylaminoethyl ester.
 Eudragit is prepared by the polymerization of acrylic
and methacrylic acids or their esters, e.g., butyl ester
or dimethylaminoethyl ester.
 Eudragit RL and RS are copolymer synthesized from
acrylic and methacrlic acid esters with a low content
of quaternary ammonium groups.
 These polymers produce films for the delayed action
preparations.
 Eudragit L and Eudragit S are the two forms of
commercially available enteric acrylic resins.
 The K value is greatly influenced by the
molecular weight distribution of the polymer
sample used in the determination.
 M= molecular weight
 Substance T (K)
Acetylene 192.40
Ammonia 195.40
Argon 83.81
Butane 134.60
Carbon (graphite) 4765.00
Carbon dioxide 216.55
Carbon monoxide 68.10
Neon 24.57
Nitric oxide 109.50
Nitrogen 63.18
Nitrous oxide 182.34
Oxygen 54.36
Palladium 1825
Platinum 2045
Sulfur dioxide 197.69
Titanium 1941.00
Uranium hexafluoride 337.17
Water 273.16
Xenon 161.30
Zinc 692.65