Professional Documents
Culture Documents
TMS Tetramethylsilan
CH3
CH3 – Si - CH3
CH3
NMR is ‘quantitative’
The intensity is measured as the integral below the
resonance signal. The intensities are proportional to the
number of protons, that contribute to the signal.
Each Particular Arrangement of Nuclei has a Characteristic
Coupling Pattern n Neighbors – (n+1) Lines
A–B
B–A –B
C–B–A
example
CH2 CH3
~50% - 50%
D Glucose
FT NMR
‘Pulse Echo’ NMR
‘Broadband Excitation’
Record ‘Transient
Response’
FID Free Induction Decay
Extract Frequencies by
Fourier Transform to get
NMR Spectrum
More Complex Experiments
Measurement of Relaxation Times (‘Lifetimes’)
Inversion Recovery
?
?
C NMR Spectroscopy
13