Treatment of premature ejaculation by Dapoxetine in Georgia: Pro et Contra

Marshania, Z.1,3,; Chochnidze N.2, , Injgia M.2,, Datashvili G. 1

1. Faculty of Medicine of Georgian National University – SEU, Tbilisi, Georgia
2. Faculty of Psychology of ilia State Uuniversity Tbilisi, Georgia
3.Department of Sexual Medicine of “Enmedic” Clinic, Tbilisi, Georgia

Objective: Premature ejaculation means to finish sexual
intercourse no more than 1 minute after vaginal penetration
(which corresponds to about 60 frictions) and the inability to
control the ejaculation. As a rule, premature ejaculation causes
in males and their partner women a feeling of lack of sexual
satisfaction and lack of overall satisfaction, and as a result
serious sexual disharmony and a sharp decline in quality of life.
For the treatment of premature ejaculation is widely used of
serotonin selective reuptake inhibitors, including dapoxetine.
Results: Dapoxetine therapy has increased the time of
ejaculation for all of 26 patients. The total PEP profile
scores has statistically reliable (P <0,001) increased
from 5.71 +/- 0,209 to 13,19 +/- 0,745. At the same time
ejaculation control, patients' concerns by reduce the
quality of life and the negative problems with a partner
were improved too.

Conclusion: As a result of our research has enabled us

to prepare a successful Georgian edition of Premature
Ejaculation Profile questionnaire as well as the
successful testing of such questionnaire. The study of
the use of 30 mg. dapoxetine 2 hours before the sexual
intercourse testifies to high efficiency and safety of the
above-mentioned treatment. However, in the conditions
of Georgia, treatment by dapoxetine was linked to the
serious problem such is high price of this medication,
which greatly hindered the patients' access to the above
mentioned drug and practically excluded its regular and
widely used clinical practice.

Methods: In our clinic we used 30 mg. of dapoxetine two

hours before sexual intercourse. Such treatment was
prescribed for 36 Georgian men with premature ejaculation.
Their age ranged from 21 to 51 years. Above-mentioned
treatment performed for 26 patients (72%). 10 patients (28%)
refused to take dapoxetine because high price of this
medication. The assessment of the effectiveness of treatment
for patient with premature ejaculation after dapoxetin therapy
was carried out by psychometric questionnaire the Premature
Ejaculation Profile (PEP) with a comprising four questions and
evaluated the subjective feelings of the patient by a five-
scores scale (from 0 to 4). It was included the control of
ejaculation, the emotional frustration caused by premature
ejaculation, the inter-personal relationships with the sexual
partner and the satisfaction with the sexual life