THEORIES OF AGING

Based on information in: Madison,

H.E. (2002).“Theories of Aging”. In
Lueckenotte, A.G. (ed), Gerontologic
Nursing. St. Louis: Mosby.
Theories of Aging:
attempt to explain the phenomenon of aging as
it occurs over the lifespan

– aging is viewed as a total process that begins at

conception
– senescence: a change in the behavior of an
organism with age leading to a decreased power of
survival and adjustment
Theories of Aging: Types

 Biologic

 Sociologic

 Psychologic

 Moral/Spiritual
Biologic Theories:

Concerned with answering basic questions

regarding the physiological processes that
occur in all living organisms as they
chronologically age
Foci of Biologic Theories

Explanations of:
– 1) deleterious effects leading to decreasing function
of the organism

– 2) gradually occurring age-related changes that are

progressive over time

– 3) intrinsic changes that can affect all member of a

species because of chronologic age
ALSO:
– all organs in any one organism do not age at
the same rate

– any single organ does not necessarily age at

the same rate in difference individuals of the
same species
Biologic Theories: Divisions

Stochastic: Explain aging as events that

occur randomly and accumulate over time

Nonstochastic: View aging as certain

predetermined, timed phenomena
Stochastic Theories

Error Theory Free Radical Theory

Cross-Linkage Theory

Wear & Tear Theory

Error Theory

Originally proposed in 1963

Basis: 1)errors can occur in the transcription
in any step of the protein synthesis of DNA
– 2) error causes the reproduction of an enzyme or
protein that is not an exact copy
– 3) As transcription errors to occur, the end
product would not even resemble the original
cell, thereby compromising its functional ability
Error, cont’d

More recently the theory has not been

supported by research
– not all aged cells contain altered or
misspecified proteins

– nor is aging automatically or necessarily

accelerated if misspecified proteins or
enzymes are introduced into a cell
Free Radical Theory
Free radicals are byproducts of
metabolism--can increase as a result of
environmental pollutants
When they accumulate, they damage cell
membrane, decreasing its efficiency
The body produces antioxidants that
scavenge the free radicals
Free Rads, cont’d

In animal studies, administration of

antioxidants postpones the appearance of
diseases such as cardiovascular disease and
CA

Free radicals are also implicated in the

development of plaques associated with
Alzheimer’s
Cross-Linkage Theory

Some proteins in the body become cross-

linked, thereby not allowing for normal
metabolic activities

Waste products accumulate

Result: tissues do not function at optimal

efficiency
C-L Theory, cont’d

Some research supports a combination of

exercise and dietary restrictions in helping
to inhibit the cross-linkage process
Wear & Tear Theory

Proposed first in 1882

Cells simply wear out over time because of

continued use--rather like a machine

Would seem to be refuted by the fact that

exercise in OA’s actually makes them MORE
functional, not less
Nonstochastic Theories:

Programmed Theory

Immunity Theory
Programmed (Hayflick Limit)
Theory
Based on lab experiments on fetal fibroblastic
cells and their reproductive capabilities in 1961

Cells can only reproduce themselves a limited

number of times.
Life expectancies are seen as preprogrammed
within a species-specific range
Immunity Theory

Immunosenescence: Age-related functional

diminution of the immune system

Lower rate of T-lymphocyte (“killer cells”)

proliferation in response to a stimulus

& therefore a decrease in the body’s defense

against foreign pathogens
Immunity, cont’d

Change include a decrease in humoral immune

response, often predisposing older adults to:
– 1)decreased resistance to a tumor cell challenge
and the development of cancer
– 2) decreased ability to initiate the immune process
and mobilize defenses in aggressively attaching
pathogens
– 3) increased susceptibility to auto-immune diseases
EMERGING THEORIES OF
AGING

Neuroendocrine Control (Pacemaker)

Theory

Metabolic Theory/Caloric Restriction

DNA-Related Research
Neuroendocrine Control

“…examines the interrelated role of the

neurologic and endocrine systems over the
life-span of an individual”. (p. 24)

there is a decline, or even cessation, in

many of the components of the
neuroendocrine system over the lifespan
Neuro, cont’d

Research has shown

– 1) the female reproductive system is controlled
by the hypothalamus. What are the
mechanisms that trigger changes?
– 2) adrenal glands’ DHEA hormone
– 3) melatonin (from pineal gland)--a regulator of
biologic rhythms and a powerful antioxidant.
Declines sharply from just after puberty
Metobolic Theory of Aging
(Caloric Restriction)
“…proposes that all organisms have a finite
amount of metabolic lifetime and that
organisms with a higher metabolic rate have
a shorter lifespan”. (p. 24)

Rodent-based research has demonstrated that

caloric restriction increases the lifespan and
delays the onset of age-dependent diseases
DNA-Related Research

Major Developments:

– Mapping the human genome (“…there may be

as many as 200 genes responsible for
contolling aging in humans”)

– Discovery of telomeres
SOCIOLOGIC THEORIES OF
AGING

Disengagement Theory
Activity/Developmental Task Theory
Continuity Theory
Age Stratification Theory
Person-Environment Fit Theory
Changing FOCUS of Sociological
considerations of aging:
– 60’s focus on losses and adaptation to them
– 70’s broader global, societal, and structural
factors influencing lives of OA’s
– 80’s-90’s exploration of interrelationships
between OA’s and their physical, political,
environmental & socioeconomic mileau
Disengagement Theory

Cumming & Henry--1961

Aging seen as a developmental task in and of
itself, with its own norms & appropriate
patterns of behavior
“appropriate” behavior patterns involved a
mutual agreement between OA’s and society
on a reciprocal withdrawal.
No longer supported
Activity Theory (Developmental
Task Theory)
Havighurst, Neugarten, Tobin ~1963

“Activity is viewed by this theory as

necessary to maintain a person’s life
satisfaction and a positive self-concept”.
(p.27)
Activity, cont’d

Theory based on assumptions:

– 1) it’s better to be active than inactive

– 2) it is better to be happy than unhappy

– 3) an older individual is the best judge of his

or her own success in achieving the first two
assumptions
Continuity Theory

How a person has been throughout life is

how that person will continue through the
remainder of life

Old age is not a separate phase of life, but

rather a continuation and thus an integral
component
Age Stratification Theory

Riley--1985
Society consists of groups of cohorts that age
collectively
The people & Roles in these cohorts change &
influence each other, as does society at large
Thus, there is a high degree of interdependence
between older adults & society
Person-Environment Fit Theory

Lawton, 1982
Individuals have personal competencies
that assist in dealing with the environment:
– ego strength
– level of motor skills
– individual biologic health
– cognitive & sensory-perceptual capacities
P-E Fit, cont’d

As a person ages, there may be changes in

competencies & these changes alter the
ability to interrelate with the environment

Significant implications in a society that is

characterized by constantly changing
technology
PSYCHOLOGIC THEORIES
OF AGING
 Maslow’s Hierarchy of Human Needs

 Jung’s Theory of Individualism

 Erikson’s Eight Stages of Life

 Peck’s Expansion of Erikson’s Theory

 Selective Optimization with Compensation
Maslow’s Hierarchy of Human
Needs
Maslow--1954
“…each individual has an innate internal
hierarchy of needs that motivates all human
behaviors”. (p. 29

depicted as a pyramid; the ideal is to achieve

self-actualization, having met all the “lower”
level needs successful
“Maslow’s fully developed, self-actualized
person displays high levels of all of the
following characteristics: perception of
reality; acceptance of self, others, and nature;
spontaneity; problem-solving ability; self-
direction; detachment and the desire for
primacy; freshness of peak experiences;
identification with other human beings;…….
…satisfying and changing relationships
with other people; a democratic character
structure; creativity; and a sense of values.

Only about 1% of us are truly ideal self-

actualized persons
Jung’s Theory of Individualism

Carl Jung--1960
origins are Freudian
Self-realization is the goal of personality
development
as individual ages, each is capable of
transforming into a more spiritual being
Erikson’s Eight Stages of Life

1993
Stages throughout the life course. Each
represents a crisis to be resolved.
For OA’s:
– 40 to 65 (middle adulthood): generativity
versus self-absorption or stagnation
– 65 to death (older adulthood): ego integrity
versus despair
Erikson, cont’d

“Self-absorbed adults will be preoccupied with

their personal well-being and material gains.
Preoccupation with self leads to stagnation of
life”
“Unsuccessful resolution of the last crisis may
result in a sense of despair in which individuals
view life as a series of misfortunes,
disappointments, and failures”. (p.30)
Peck’s Expansion of Erikson’s
Theory
Erikson’s last two stages are expanded to 7
The final three of the developmental tasks
for old age:
– ego differentiation versus work role
preoccupation
– body transcendence versus body
preoccupation
– ego transcendence versus ego preoccupation
Selective Optimization with
Compensation
Baltes--1987

Individuals develop strategies to manage

losses of function that occur over time
Selective Optimization, cont’d

3 Interacting Elements:
– selection: increasing restriction of one’s life to
fewer domains of functioning
– optimization: people engage in behaviors to
enrich their lives
– compensation:developing suitable, alternative
adaptations
 THE END!

Thanks for hanging in there!