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Meningioma

Derived from arachnoid cap cells of the arachnoid mater.

Most common location: along the falx, the convexities (i.e., over the cerebral hemispheres), and
the sphenoid wing.
Less common locations: foramen magnum, olfactory groove, and inside the lateral ventricle.

Slow growing, encapsulated, benign tumor


Etiology & Risk Factor
• Ionizing Radiation
• Obesity
• Occupational (Pesticide/Herbicide)/Diet/Allergies
• Hormones
• Molecular characteristics
Sign and Symptoms
The presentation of meningiomas are often non-specific, but location and compression of adjacent
brain and vascular structures can lead to focal neurologic deficits (including cranial nerve deficits).
Symptoms that are commonly seen are as follows:
• headache (33.3–36.7%),
• focal cranial nerve deficit (28.8–31.3%),
• seizure (16.9–24.6%),
• weakness (11.1%),
• vertigo/dizziness (9.8%),
• ataxia/gait change (6.3%),
• pain/sensory change (5.6%),
• syncope (1.0%),
• asymptomatic (9.4%).

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