Improve diagnostics of Cancer

through Artificial Intelligence and

Digital Pathology
OLS5 Graduation
20/07/2022 (Online)

Project team: Stephane Fadanka, Elisee Jafsia, Nodira Ibrogimova

Mentor: Sebastián Ayala Ruano
Cancer incidence and deaths forecasted to rise fastest in The Problem
Africa compared to other world regions!!!

⮚ 70% of deaths from cancer occur

in low- and middle-income
countries.
⮚ Diagnosis of cancer relies on
histology in nearly 80% of cases.
⮚ Shortage of clinicians and
pathologists available for cancer
diagnosis and treatment.
⮚ No necessary data to drive
cancer policies.
⮚ Inaccessible diagnosis
and treatment are ⮚ Diagnosis of cancer relies on histology in
common. nearly 80% of cases
⮚ Lack of correct and ⮚ Digital microscopy and telepathology
timely diagnosis of were successfully used to mitigate the
specimens by lack of pathologists in Cameroon, thus
pathologists confirming the availability of a robust
dataset for our project
⮚ Late-stage presentation

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 Our Solution
We propose a hybrid diagnosis method combining Microscopy and ML/AI
algorithms.

Develop a rapid, highly sensitive diagnostic tool for the diagnosis of breast cancer, to increase cancer
treatment efficacy and reduce overtreatment of tumors clinically suspicious for malignancy.

Open-source project

Reliable and fast diagnostic tool (Combining AI, ML and Microscopy)

Generating and Using useful Data

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 Progress and Vision
Done .| Ongoing |.
• Project website
• Project Documentation • Building Community
• GitHub Project Page (Users/Developers)
1 3
Next >>
Apply developed AI model Adapt to other
in real life setting Cancers or Diseases
5 7

2 4 6

• Algorithms Create project AI Keep training the

Developed dataset Algorithms
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 OLS 5 Experience
Collecting a large amount of data when tackling a completely new task can be challenging, to say the least.

However—

Obtaining satisfactory model performance (think: model accuracy) using only a limited amount of data for
training is also tricky... if not impossible.

Fortunately, there is a solution that addresses this very problem, and it goes by the name of Transfer Learning.

The Steps in Transfer learning are:

1. Obtain pre-trained model

2. Create a base model
3. Freeze layers
4. Add new trainable layers
5. Train the new layers
6. Fine-tune your model

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OLS 5 Experience
❑ Open Source Project Management:
Documentation and resources
❑ Project Lisence

❑ Git/GiHub (Readme file)

Challenges | Solution
1. Time zone difference | Flexible time slots
2. Logistic issues (Stable Internet and Meeting tools) | OLS
Microgrants ❏ Networking and live Collaboration:
3. IT Literacy | Flexible tools 6
Ersilia visit at Mboalab (07/2022)
Thanks! All Experts and Speakers!!!

Organizers: Mentor:
Sebastián Ayala Ruano
● Yo Yehudi
● Emmy Tsang
● Malvika Sharan OLS’ers:
Entire OLS community
● Bérénice Batut

National Cancer Institute (USA.gov)

Stephane Fadanka EliseeJafsia Nodira Ibrogimova

★ Stephanefadanka@gmail.com ★ jafsiaelisee@gmail.com ★ nodira.ibrogimova@gmail.com
★ https://github.com/Fadanka ★ https://www.github.com/jafsia ★ https://github.com/NodiraIbrogimov
★ @StephaneFadanka ★ @euclude ★ @NodiraDeveloper 7