ENDOMETRIAL

CYTOLOGY
PRACTICALS
AMA AFRAH
 ESSENCE OF ENDOMETRIAL
CYTOLOGY?
• INFECTION OF UTERUS

• MONITOR TREATMENT

• SCREENING PURPOSES:INFERTILITY

• POST MENOPAUSAL BLEEDING

WHEN IS IT NORMAL TO HAVE ENDOMETRIAL
CELLS IN VAGINAL AND CERVICAL SECRETIONS
CONSIDERING THE ENDOMETRIAL

• 1-12 DAY FROM THE START OF MENSTRUATION: NORMAL

MENSTRUAL CYCLE

• TIMING CANNOT BE USED:MENORRHAGIA, IRREGULAR MENSTRUAL

PERIOD, IUCD IN UTERUS
• FUNCTIONALIS SLOUGHS OFF WITH MENSTRUAL, REPLACED BY
BASALIS OR BASAL LAYER
HOW DO YOU DISTINGUISH ENDOMETRIAL FROM
ENDOCERVICAL CELLS CONSIDERING THE FACT
THAT THEY ARE BOTH COLUMNAR IN SHAPE

• ENDOMETRIAL LOOKS SMALLER ENDOCERVICAL

ENDOMETRIAL CELLS HAVE ROUND NUCLEUS AND ENDOCERVICAL HAS

END TAPING

ENDOCERVICAL CELL HAS LONGER/WIDER CYTOPLASM AND

ENDOMETRIAL HAS SCANTY CYTOPLASM
HOW TO DISTINGUISH ENDOMETRIAL
HYPERPLASIA FROM MALIGNANCY
• Both are anisokaryotic, how to you distinguish one from
another?
• CRITERIA FOR MALIGNANCY: IRREGULAR NUCLEAR MEMBRANE
ADENOCARCINOMA
ENDOMETRIAL SARCOMA