Transposition of

the Great Arteries

Case history
• Name : jethalal gadha
• Age :28 days
• Sex:Male
• Date:21/07/22
Clinical features/symptoms
Cyanosis (bluish skin, lips and nails from not getting enough oxygen-rich
blood)
Fast or labored breathing
Poor feeding.
• Rapid heart rate.
General examination
• Infants typically present with progressive central (perioral and periorbital)
cyanosis
• Central (perioral and periorbital) cyanosis. Other than cyanosis and a loud,
single second heart sound (S2), the physical examination is often
unremarkable
• No omphicel or hernia
Cardiovascular system
• The two main arteries carrying blood out of the heart – the main
pulmonary artery and the aorta – are switched in position
• Single second heart sound (S2) and a systolic ejection murmur may be
present.
Differential diagnosis
Most babies with TGA have only that defect, but there are other defects that
can occur with TGA:
Atrial septal defect (ASD)
Ventricular septal defect (VSD)
Patent ductus arteriosus (PDA)
• The above CHD can be suspected, with the help of echo we can know more
Investigation/radiograph
• CBC
• 2D echo
• CXR
Interpretation
• Normal cbc
• In echo:- transposition can be seen
• CXR blood flow disturbed
Diagnosis
• Transposition of the great Arteries
Treatment
• Before surgery for transposition of the great arteries, a medication called
alprostadil (Caverject, Edex, others) may be given to increase blood flow
and improve mixing of oxygen-poor and oxygen-rich blood
• Open heart surgery
• Surgeon will connect the aorta and pulmonary artery to their normal
ventricles. The surgeon will also have to move the coronary arteries.
Recommendations
• Consult pediatrician for any information
• Take medication on time
• TGA are usually seen during pregnancy so ask the obs/guyne as soon as
possible