DIFFERENTIAL DIAGNOSES

Leukocytosis

Benign Malignant

Bone Marrow Other

Infection Other
Disorders Malignancies

Myeloproliferative
Acute Leukemia Chronic Leukemia
Neoplasm
INFECTION (BACTERIAL/VIRAL)

RULE IN RULE OUT

• Elevated WBC • No symptoms of apparent
infection such as fever, chills,
headache, cough, colds, sore
throat, abdominal pain, dysuria,
diarrhea, erythema, swelling,
pain or tenderness
DIFFERENTIAL DIAGNOSES
Leukocytosis

Benign Malignant

Bone Marrow Other

Infection Other
Disorders Malignancies

Myeloproliferative
Acute Leukemia Chronic Leukemia
Neoplasm
OTHER BENIGN CONDITONS
• Drugs
• Corticosteroids, lithium, beta-agonists
• Emotional Stress
• Physical Stress
• Seizure, anesthesia, surgery, overexertion
• Allergic Reaction
• Chronic Inflammatory Disease
• rheumatoid arthritis, inflammatory bowel disease, or a granulomatous
disease
OTHER BENIGN CONDITONS

RULE IN RULE OUT

• Elevated WBC • No complaints of emotional or
physical stress
• No chronic inflammatory disease
• No history of drug intake
• No previous
hospitalization/surgery
DIFFERENTIAL DIAGNOSES
Leukocytosis

Benign Malignant

Bone Marrow Other

Infection Other
Disorders Malignancies

Myeloproliferative
Acute Leukemia Chronic Leukemia
Neoplasm