Journal Reading

Validation of Aspartate Aminotransferase to Platelet Ratio for

Diagnosis of Hepatic Fibrosis and Prognostic Prediction of
Infants with Biliary Atresia after Portoenterostomy

FAKULTAS KEDOKTERAN UNIVERSITAS SRIWIJAYA

RSUP Dr.MOHAMMAD HOESIN PALEMBANG
2022
 Outlines
• Background
• Methods
• Results
• Conclusion
• Critical Appraisal
• Conclusion
Background
 Methods
• Type Of Research

• Time And Place

• Population And Sample

 Methods
• Inclusion And Exclusion Criteria
 Methods
• Variable Of Research
Results
Conclusion
CRITICAL APPRAISAL
Population
• Apakah subjek penelitian diambil dengan cara
yang tepat?
• Apakah penelitian ini mempunyai jumlah
subjek yang cukup untuk meminimalisir
kebetulan?
Intervention
• Apakah data yang dikumpulkan sesuai dengan
tujuan penelitian?
Comparison
• Apakah analisa data dilakukan cukup baik?
Outcome
 Validity
Research question
• Is the research question well-defined that can be answered
using this study design?
Yes/No

• Does the author use appropriate methods to answer their

question?
Yes/No

• Is the data collected in accordance with the purpose of the

research?
Yes/No
Randomization
• Were the patients randomized to the
intervention and control groups by a well-
defined method of randomization?
Yes/No

• Was the randomization list concealed from

patients, clinicians and researchers?
Yes/No
Blinding
• Were the patients and clinicians kept blinded
(masked) to which treatment was being given?
Were they kept blinded until the end of the
study?
Yes/No
Interventions and co-interventions
• Were the performed interventions described
in sufficient detail to be followed by others?
Yes/No

• Other than intervention, were the two groups

cared for in similar way of treatment?
Yes/No
 Importance
• Is this study important?
Yes/No
 Applicability
• Are your patient so different from those studied
that the results may not apply to them?
Yes/No

• Is your environment so different from the one in

the study that the methods could not be use
there?
Yes/No
 Conclusion
This journal is valid, important, and applicable.
Thank You