• Was there an independent and blind comparison with a reference
standard?- NO • BLINDING • Did the patient sample include an appropriate spectrum of patients o whom the diagnostic test will be applied in clinical practice? NO • Represents ALL types of patients to which the test will be applied in clinical practice. • Did the results of the test being evaluated influence the decision to perform the reference standard?- No RESULT APPLICABILITY • Will the reproducibility of the test result and its interpretation be satisfactory in my setting?- Yes • Are the results applicable?-Yes • Will the results change my management?- Yes