DRUG METABOLISM

EVOCATION
 General Objective:
 
Students will be able to analyze the two chemical pathways of drug
metabolism and the factors affecting them in vivo.
 
Specific Objectives:
 
▣ Classify the two chemical pathways of drug metabolism in vivo.
(S) (U/C)
▣ Explain the two categories of drug metabolism in vivo. (S) (U/C)
▣ Outline the three chemical factors involved in drug metabolism in
vivo. (S) (An/C)
 FA1 & FA2
1.Combination of mechanisms by which a drug is irreversibly transferred
from the systemic circulation into extracorporal fluids is called as
a)Excretion b) Absorption c) Distribution d) Galenics

2)The main organs responsible for renal excretion are

a)Kidneys b) Liver c) Heart d) Lungs

3)The decline of the plasma concentration is associated solely with of drug

from the body.
a)Elimination b) Absorption c) Distribution d) Excretion

4. Drug metabolizing enyzmes are 

a)microsomal and non microsomal b)microsomal c) non
microsomal d)microenzymes
 SQ
1. Neonates are at greater risk from drug
intoxication than infants and children. Explain?
MINDMAP