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    Beer Dilacshe
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    This document discusses antitussive drugs, which are used to suppress coughing. It defines antitussive drugs as those that reduce cough center activity in the brain. There are two main types of cough - productive cough which removes excess secretions, and nonproductive or dry cough which is harmful. The types of antitussive drugs discussed are narcotic/opioid antitussives like codeine and hydrocodone, non-narcotic antitussives like dextromethorphan and benzonatate, antihistamines, and expectorants. Narcotic antitussives are most effective at suppressing cough but also carry risk of dependence, while non-narcotic varieties are less potent

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    This document discusses antitussive drugs, which are used to suppress coughing. It defines antitussive drugs as those that reduce cough center activity in the brain. There are two main types of cough - productive cough which removes excess secretions, and nonproductive or dry cough which is harmful. The types of antitussive drugs discussed are narcotic/opioid antitussives like codeine and hydrocodone, non-narcotic antitussives like dextromethorphan and benzonatate, antihistamines, and expectorants. Narcotic antitussives are most effective at suppressing cough but also carry risk of dependence, while non-narcotic varieties are less potent

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    © All Rights Reserved
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    31 views15 pages

    Cough (Antitussive) Drugs

    Uploaded by

    Beer Dilacshe
    This document discusses antitussive drugs, which are used to suppress coughing. It defines antitussive drugs as those that reduce cough center activity in the brain. There are two main types of cough - productive cough which removes excess secretions, and nonproductive or dry cough which is harmful. The types of antitussive drugs discussed are narcotic/opioid antitussives like codeine and hydrocodone, non-narcotic antitussives like dextromethorphan and benzonatate, antihistamines, and expectorants. Narcotic antitussives are most effective at suppressing cough but also carry risk of dependence, while non-narcotic varieties are less potent

    Copyright:

    © All Rights Reserved
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    of 15

     ANTITUSSIVE DRUGS

    DR. BASHIR NUR

    1
    DEFINITION
     ANTITUSSIVE:-
    A drug that suppresses coughing
    possibly by reducing the activity of the
    cough center in the brain.

    Antitussive agents are used to relief dry


    cough.

    2
    Cough
     Cough is protective reflex, its purpose being
    expulsion of respiratory secretions or foreign
    particles from the lungs and upper airway
    passages.

    3
    Two Basic Types of Cough
     Productive cough
     removes excessive secretions

     Nonproductive cough
     Dry cough and it is harmful

    4
    Types of antitussive
    1) ANTITUSSIVE
    Narcotic/opioid antitussive:-
    Codeine, Hydrocodone
    Non-narcotic/non-opioid
    antitussive:- Dextromethorphan,
    Benzonatate, noscapine

    Antihistamines
    Chlorpheniramine ,
    diphenhydramine , promethazine

    5
    Types of antitussive
    2) Expectorants(Mucokinetics)
    Mucolytics :-
    Carbocysteine,
    Bromhexine,
    Ambroxol
    Guaifenesin

    6
    Narcotic agents

    Narcotic agents have anti-tissuve effects.


    They are effective in suppressing the
    cough reflex.
    They are POM drugs.
    Their use lead dependence

    7
    Codeine
     It is a very popular narcotic anti-tissuve drug.
     It is a potentially addictive.

     Depress the CNS activity

     It is classified pregnancy category C.

     Adult dose is 10-20mg

     It is contraindicated:

    1. Hypersensitivity

    2. Respiratory depression

    3. Seizure disorders

    8
    Non-narcotic agents

     Non-narcotic antitissuve drugs are less


    effective than the narcotic ones.
     They are available either alone or
    combination with other agents, they are
    POM drugs.

    9
    Tussilar syrup

    composition
    Chlorpheniramine Maleate
    Dextromethorphan Hydrobromide

    10
    Tusskan syrup

    composition
    Guaifenesin
    Ephedrine hydrochloride
    Dextromethorphan

    11
    Bronchophane syrup

    Composition
    Guaifenesin
    Ephedrine Hydrochloride
    Diphenhydramine hydrochloride
    Dextromethorphan Hydrobromide

    12
    Dexaphen syrup

    Composition
    Dexamethasone
    Chlorpheniramine

    13
    Piriton syrup

    Composition
    Chlorpheniramine

    14
    Thank you

    15

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