TRANSDERMAL

PATCHES

BY GROUP FOUR
 OUTLINE OF PRESENTITAON
HISTORY OF TRANSDERMAL PATCHES

PRINCIPLE OF OPERATION

Areas of APPLICATION/ USES

MERITS AND DEMERITS

CONCLUSION

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 BACKGROUND
A transdermal patch is a medicated adhesive patch placed on the
skin to deliver a specific dose of medication into the blood stream.

It is a non-invasive technique and favours drugs that undergoes

first pass metabolism.

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 COMPONENTS OF TRANSDERMAL
PATCHES

1 2 3 4 5

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 MERITS AND DEMERITS
MERITS DEMERITS
1. It is advantageous to patients who are 1.Possibility of local irritation at the site of
unconscious or feeling nauseating. application.
2. It is good for drugs that undergoes first pass 2. May cause allergic reactions.
metabolism. 3. Only medications of lower molecular weight
3. Drugs that can cause gastrointestinal upset can permeate the skin.
are good candidates
4. It’s good for drugs that can easily be
degraded by enzymes in the gastrointestinal
system.

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 AREAS OF APPLICATION
-The transdermal patch is applied at the stratum corneum of the skin to deliver medications
directly into the bloodstream.

- They are used to treat wounds at specific locations on the skin.

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 PRINCIPLE OF OPERATION OF TRANSDERMAL
PATCHES

The transdermal patch acts as a carrier for drugs, holding it until

it’s applied to the skin.
The patch's adhesive binds it to the skin at the time of application,
and the medications it contains will start to enter the
bloodstream.
The patch will continue to supply the required amount of
medication until is completely used up or the plaster is removed.

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 TRANSDERMAL ABSORPTION
PASSIVE
This method rely on natural diffusion to
transfer the medication from the patch into
the blood stream of the patient.
This provide a uniform transfer depending
on the characteristics of the skin and the
design of the patch.
ACTIVE
Active on the other hand uses other
enhancers of permeators or microneedles to
administer to the skin.
Here, the amount of diffusion depends on

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Thank you