Microwave Irradiation Technique: A Green Extraction Method for

Isolation of Phytoconstituents from Medicinal Plants

Category : Engineering and Technology Level : UG

01 ABSTRACT
Natural components are important sources for drug development. The amounts To extract various phytochemicals
of bioactive natural components in natural medicines are always fairly low. 01 from crude drugs using MAE.
Today, it is very crucial to develop effective and selective methods for the
extraction and isolation of those bioactive natural components. The aim of this

02
To compare the properties of MA
study was to increase extraction rate, yield and quality of products, associating
microwave field with extraction of plant’s active compounds. Compared to
02 extracted phytochemicals with other
conventional extraction techniques.
classical hot extraction methods (CE), microwave extraction (MAE) provides
higher purities in active compounds while avoiding local over-exposure, very
important assets for industry. Extracted Phytoconstituents from five different
AIM To replace conventional extraction
medicinal plants were analyzed for various parameters.
03 techniques with Advanced MAE.

03 EXTRACTION PRINCIPLE 05
Moisture Tremendous
Swelling Leaching
Nature of crude drug
1 5 Microwave power
Matrix
Microwave
radiation
get
heated
Moisture
evaporates
pressure
generated on
of plant
cell
Rupture
of the cell
out of
Phyto-
Nature of solvent
2 Factors
6 characteristics

3 7 Temperature
cell wall constituents Volume of Solvent
up governing
Nature of Target
Extraction Time 4 8 molecule
04 EXPERIMENTAL DESIGN
Sr. Plant
Time Taken
Analyte Solvent
% Purity obtained
06
No Material
MAE Soxhlet Maceration MAE Soxhlet Maceration TLC
1 Turmeric Rhizome 10 min 6 hrs 3-4 days Curcumin EtOH 93 69 40 Curcumin GA ANALYSIS
2 Neem Leaves 24 2 days 4 days Nimbolide Acetate/Hexane 98 72 52
(4:6)
3 Clove Flower Bud 4min 7hrs 4days Eugenol EtOH/H2O 94 70 40

Glycyrrhizic EtOH/NH3
4 Liquorice Root 4-5 min 8hrs 3 days acid  89 62 50
(6:1)

Cinnamaldeh
5 Cinnamon Bark 50 min 6hrs 3 days Water 92 73 41

08 CONCLUSION
yde
Improved Extraction Yield
Low Solvent Consumption
09 REFERENCES
01

Compared to classical hot extraction

07 02 Microwave-assisted Extraction for
Time Saving methods (CE), microwave extraction (MAE) Bioactive Compounds: Theory and Practice

OUTCOMES
03
1 provided higher purities and extraction
yields in active compounds while avoiding 1
2013th Edition, Kindle Edition, Springer
Publications
04
High Purity local over-exposure. Recent Advances in Microwave Assisted
05
2
Extraction of Bioactive Compounds from
Automated Complex Herbal Samples: A Review,
06

2 Hence, MAE is a green approach to replace Critical Reviews in Analytical Chemistry,

Method suitable for Thermolabile Volume 51, Issue 8 (2021)
conventional extraction techniques.
phytoconstituents