TRANING PERIOD IN VISA DRUGS & PHARMACEUTICALS BADDI (HP)

Presented by: Harwinder Kumar Roll No. 81307421017 Address :- V.P.O Khera, pin code 146106,Dist Hoshiarpur. Contacts - 01884242575, +919464065575. Email Id:- harwinderpandit@yahoo.com harwinderpandit@hotmail.com

Collage:- RAYAT BAHRA INSTITUTE OF PHARMACY (Hoshiarpur, PUNJAB) Site:- http://home.rayatbahra.com/

CONTENTSCONTENTSy

1. TABLET SECTION

2. CAPSULE SECTION

3. PACKAGING SECTION

Instruments1. Paste kettle 2. RMG (Rapid Mixer Granulator) 3. FBD (Fluid Bed Dryer) 4. Vibro Sifter 5. Multimill 6. Blenders ( Double Cone Blender & octagonal blender) 7. Tablet Compression Machine 8. Tablet Coating Pan

Working of Compression Machine

Problems during Tablet Compression

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CAPPING & LAMINATION- Capping

is defined as the splitting of one or both lids of a tablet from its body. Lamination is similar to capping but here the tablet gets separated into layers. MOTTLING-Mottling is uneven distribution of the colour on the surface of the tablet, with dark and light patches on it. STICKING - It refers to the sticking of the tablet material with the die walls results in rough edges of tablet PICKING- Picking happens when a part of the tablets gets sticks to the punch surface and gets eroded from the tablet surface.

Capsule Filling & sealing Machine

Capsule Polishing Machine

THE FIRST STATION:ORIENTATION OF CAPSULE The functions of first station include capsule feeding, aligning and insertion into bores of holding ring . Also, vacuum is used for separating capsule cap and body in first station. After orientation of capsule, capsule cap can stay in upper holding ring and capsule body can stay in lower holding ring.

Separate the holding ring , put the lower (body) holding ring on the rotary table, pull the powder hopper over the lower (body) holding ring, then auger inside powder hopper starts to run and fill powder into the capsule body. While Iower holding ring turns one circle, push powder hopper to its original position.

Put upper holding ring and lower holding ring together, then take the holding ring ahead of ejector and aim ejector at the bores of holding ring . Use hydraulic cylinder to push ejector and let it press capsules for closing. Finally push capsules inside the bores of holding ring out, the finished capsules will be collected into the container.

 LOCKING

If the empty shell capsules are

locked then they will not open into the holding rings and powder filling does not occurs.

Denting Denting of cap or body is occur during locking when locking is not properly occurred (due to increase in hydraulic pressure during locking).

In this packing one side of tablet stripes is PVC (Poly vinyl Chloride) and another side is alumininum foil is used. 1.PVC FOILS- 1. PVC (Poly vinyl Chloride) foil 2. PVDC(poly vinyl dichloride foil) foil. Thickness of PVC foil 0.250mm. 2. ALUMINIUM FOIL Thickness of aluminum foil 0.075mm.

In which both side of tablet/capsule strips aluminium foil is used. Thickness of alu. Foil - 0.020mm to 0.045mm