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BLOOD

neutrophil
Eosinophils in Immune Regulation
Activated eosinophils are a heterogeneous
population of cells, with variable granular,
cytokine, chemokine, and surface phenotypes,
compatible with a range of functional states. 
eosinophil
Basophils
The strong basophilia is due to the
Presense of heparin and other sulfated
GAGs,histamine,platlet activating factor
Phospholipase.
basophil
monocyte
lymphocyte
lymphocyte
hematopoesis
Eosinophils develop from the multipotential myeloid stem cell (CFU-
GEMM) which differentiates into eosinophilic progenitor cells (CFU-
Eo).
Eosinophilic myeloblasts are produced directly from progenitor cells
(CFU-Eo) under the influence of cytokines. The eosinophilic
myeloblast matures into an eosinophilic promyelocyte. These cells
cannot be distinguished from cells at the same stage in other
granulocyte lineages. (See MH034B Neutrophil Development for
these earlier stages.)
Eosinophilic myelocyte is the first recognizable precursor of
eosinophils.
Large cells (18 to 20 µm diameter)
Round, oval, or indented nucleus (50% of cell) with a coarser,
granular pattern of chromatin
Cytoplasm is pale blue
Very eosinophilic, specific granules begin to accumulate
Azurophilic granules
Last cell capable of mitosis

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