02 Literature

Review
Definition Etiology
Acute rheumatic fever (ARF)

• results from the body’s autoimmune response to a

throat infection caused by group A Streptococcus
bacteria
• causes a general inflammatory response and disease
that selectively affects the heart, joints, brain and
skin

S. Pyogenes
Epidemiology
336.000 New cases per year

Mortality rate per year

1,5%

ARF >> RHD •

•
0.3 to 0.8 per 1,000 children.
2007 there were 10.408 ARF patients who
60% If not detected or do not get the right were hospitalized and 952 outpatient care
therapy
Pathophysiology
Risk factors

01 03
Genetic Environtment

02 04
Age Nutrional status