OUTLINE OF LECTURE • Introduction to consciousness and altered mental status • Causes of altered mental status • Hypoglycemia as cause of altered mental status • Approach to examination and management of altered mental status. OBJECTIVES OF LECTURE • Understand the meaning of altered mental status condition • Know the causes of altered mental status • Able to elicit possibility of hypoglycemia as cause of altered mental status • Able to manage patient with altered mental status. CONSCIOUSNESS • CNS functions – Voluntary movements – Interpretation and integration of sensation – Consciousness – Cognitive function • Consciousness – Awareness of self and environment ALTERED MENTAL STATUS INTRODUCTION • Altered mental status – Alteration in higher cerebral functions – memory, attention or awareness. – Ability to sustain and focus attention is impaired. • Potential life threatening condition • Etiology might be chronic or acute, reversible or irreversible. • Many different organ systems might be implicated ALTERED MENTAL STATUS COMMON CAUSES • Hypoglycemia • Poisoning • Post seizure • Infection • Head trauma ALTERED MENTAL STATUS PATIENT APPEARANCE • Intoxicated appearance, staggering, slurred speech to complete unresponsiveness • Uncharacteristic behavior – Anxious or combative • Seizures ALTERED MENTAL STATUS HYPOGLYCEMIA • An abnormally low level of glucose in the blood. • Usually occur in people with diabetes mellitus – Treated with hypoglycaemic drugs or insulin • Mechanism of hypoglycemia in diabetics – Too high a dose of medications – Diabetic person misses a meal or takes strenuous exercise. HYPOGLYCEMIA CLUES TO HYPOGLYCEMIA • Past illness of diabetes mellitus • Medications history – Insulin pen – Diabetic medications • Rapid onset of altered mental status – Patient on medication but miss a meal – Patient on medication but unable to tolerate orally – poor appetite or vomiting or fever – After an unusual exercise or physical work episode HYPOGLYCEMIA HYPOGLYCEMIA SYMPTOMS • Hunger • Dizziness • Headache, • Confusion – Behaviour is often irrational and aggressive. – Coma in severe cases. HYPOGLYCEMIA SIGNS • Elevated heart rate • Cold, clammy skin • Sweating • Dizziness • Trembling • Coma may occur in severe cases. ALTERED MENTAL STATUS AMPLE HISTORY • Allergies if any • Medications – Diabetic medications – Drugs that cause drowsiness – sleeping pills, psychiatric medications – Drugs of abuse – morphine, heroin • Past illness – Diabetes mellitus – Epilepsy • Last meal ALTERED MENTAL STATUS AMPLE HISTORY • Events related to altered mental status – Onset when it started – Any other features – fever, seizures, headache – History of trauma ALTERED MENTAL STATUS PRIMARY SURVEY • Establish responsiveness of patient • Pay attention to airway and breathing – Patient with poor consciousness level may not be able to protect airway – Examine for features of airway obstruction or breathing difficulties • Circulation – Look for features of poor perfusion ALTERED MENTAL STATUS INTERVENTION • In unresponsive patient – Open the airway and provide oxygen • Initiate ventilation using bag-mask method if inadequate breathing • If patient has history of diabetes and hypoglycemia features suspected on history – Obtain medical direction for oral glucose administration – protocol guided. APPROACH TO PATIENT MONITORING AND COMMUNICATIONS • Altered mental status considered as emergency – vital signs monitoring every 5 minutes – Mental status – Airway patency – Breathing for rate and quality – Pulse for rate and quality. • Communicate with base – Medical direction for medication – Patient-related information – Intervention related information PRE-HOSPITAL CARE TRANSPORTATION • Patient must be transported to medical facility • Further monitoring required – Oral hypoglycemic agents have long duration of action – Other causes must be ruled out. PRE-HOSPITAL CARE SUMMARY • Altered mental status – alterations in higher cerebral functions • Potential life threatening condition which many different organ systems might be implicated • Hypoglycemia is a reversible cause if treated early