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Orthopedic Trauma

considerations

Abraham Tarekegn
Lecturer, Department of Anesthesia
CMHS, University of Gondar
Outline
 Introduction

 Comparison of GA vs RA for orthopedic trauma

 Fat embolism syndrome

 Compartment syndrome

 crush syndrome

 VTE
Objectives
o Upon completion of this session you will be able to:

Describe special anesthetic issues related to orthopedic


trauma.

Utilize appropriate anesthesia options for OT.

Analyze advantages of one anesthetic technique over


the other.
Introduction

• Musculoskeletal injuries are the most frequent indication for


surgery in most trauma centers.

• Because many procedures can be appropriately managed


under RA, familiarity with these techniques is essential.
Introduction …
• The length of many procedures necessitates attention to:
 Body positioning,

 Maintenance of normothermia,

 Fluid balance and

 Preservation of peripheral blood flow


Introduction …
• Emphasis in trauma management of a multiple trauma patient
has included early stabilization of long-bone, spine, pelvic, and
acetabular fractures.

• Failure to do so results in:


 Increased morbidity,

 Pulmonary complications and

 Length of hospital stay


Advantages & Disadvantages of RA
for Trauma Patients
Advantages
o Allows continued assessment of mental status
o Increased vascular flow
o Avoidance of airway instrumentation
o Improved postoperative mental status
o Decreased blood loss
o Decreased incidence of DVT
o Improved postoperative analgesia
o Better pulmonary toilet
o Earlier mobilization
RA for trauma…

Disadvantages
o Peripheral nerve function difficult to assess
o Patient refusal common
o Requirement for sedation
o Hemodynamic instability with placement
o Longer time to achieve anesthesia
o Not suitable for multiple body regions
o May wear off before procedure(s) conclude
Advantages and Disadvantages of
GA for Trauma Patients
Advantages
o Speed of onset

o Duration—can be maintained as long as needed

o Allows multiple procedures for multiple injuries

o Greater patient acceptance

o Allows positive-pressure ventilation


GA for trauma…

Disadvantages
o Impairment of global neurologic examination

o Requirement for airway instrumentation

o Hemodynamic management more complex

o Increased potential for barotrauma


Compartment syndrome
o Compartment syndrome of the extremities is

 a condition in which increased pressure within a limited space


compromises the circulation and function of the tissues within that space.

o In orthopedic trauma the most common cause of compartment


syndrome is edema secondary to muscle injury and associated
hematoma formation.

o Though most commonly associated with traumatic injuries.


Compartment syndrome …

o Compartment syndrome occurs when the pressure within an


osteofascial compartment of muscle causes ischemia and then
necrosis.

o Compartment syndrome can also occur as a result of a number of causes

associated with trauma including:


 reperfusion injury, burns, drug overdose, and prolonged limb compression
Compartment syndrome …

o The most common fractures associated with the

development of compartment syndrome are those of:


 the tibial shaft (40%) and

 forearm (18%).

o A further 23% are caused by soft tissue injuries without fracture


Risk Factors for The Development of
Compartment Syndrome
Compartment syndrome …

o The classic hallmarks of compartment syndrome have been


described as the “five P's.”
 pulselessness,

 pallor,

 paralysis,

 paresthesia, and

 pain
Compartment syndrome …
Management

o Fasciotomy is the only treatment for acute compartment syndrome.

o Fasciotomy is a surgical procedure where the fascia is cut to relieve


tension or pressure commonly to treat the resulting loss of
circulation to an area of tissue or muscle.

o The muscle compartment is cut open to allow muscle tissue to swell,


decrease pressure and restore blood flow.
Compartment syndrome …

o Fasciotomy:

 When compartment Pressure approaches 20 to 30 mm Hg below DBP,

 Worsening clinical condition,

 Documented rising tissue Pressure,

 Major soft tissue injury, or

 History of 4 - 6 hours of total ischemia.


Fat embolism syndrome

o Most patients undergoing long-bone fracture manipulation


experience microembolism of fat & marrow.

o No visible problem on most patients, but some will experience a


significant acute inflammatory response.

o Some lung dysfunction occurs in almost all patients (from minor


laboratory abnormalities to FES).
Fat embolism syndrome …

o Clinically significant FES occurs in 3% to 10% of patients.

o FES is classically seen in patients with long bone fractures who develop
sudden tachypnoea and hypoxia. Although sometimes a petechial rash is
seen (check conjunctiva).

o Signs include hypoxia, tachycardia, mental status changes, and a petechial


rash on the upper portions of the body.

o 1 Major and 4 minors (as defined by Gurd) .


Criteria for Diagnosis of FES

Major (at least one)

o Axillary/subconjunctival petechiae

o Hypoxemia (Pao2 <60 mm Hg; FIO2 <0.4)

o CNS depression (disproportionate to hypoxemia)

o Pulmonary edema
Criteria for Diagnosis of FES …
Minor (at least four)
o Tachycardia (>110 beats/min)

o Hyperthermia

o Retinal fat emboli

o Urinary fat globules

o Decreased platelets/hematocrit (unexplained)

o Increased erythrocyte sedimentation rate

o Fat globules in sputum


Criteria for Diagnosis of FES …

o Laboratory

 Thrombocytopenia.

 Sudden decrease in hg by 20%.

 Raised ESR.

 Fat macroglobulaemia.
Criteria for Diagnosis of FES …
o FES should be considered whenever the alveolararterial O2 gradient
deteriorates together with decreased pulmonary compliance & CNS
deterioration.

o Under GA, the CNS changes will not be apparent but may be
manifested as delayed awakening.

o Diagnosis in the OR is largely based on the clinical findings after ruling


out other causes of hypoxemia.
Treatment of FES

 Early resuscitation and stabilization are vital.

 Early O2 therapy may prevent onset of syndrome.

 May require mechanical ventilation (10–40% of patients).

 Steroid

 FES usually resolves within 7d.


Treatment of FES …
o Lung infiltrates seen on chest radiography confirm the presence
of lung injury.

o This needs appropriate ventilatory management with O2,


higher PEEP, & possible longer term MV.

o Treatment includes: early recognition, administration of O2,


and judicious fluid management.
Crush syndrome
o Is the general manifestation of crush injury caused by
continuous prolonged pressure on extremities.

o Muscle injury 2o to ischemia  Myoglobinuria  ARF &


subsequent profound electrolyte disturbances.

o The most critical treatment consists of crystalloid fluid


resuscitation.
Crush syndrome …
o Osmotic diuresis with mannitol and alkalinization of urine
with sodium bicarbonate.
o The preferred therapy for ARF 2o to rhabdomyolysis is
continuous renal replacement therapy and hemofiltration.
o Anesthetic concerns
 Myoglobinuria  ARF
 Electrolyte disturbance (K)
 Fluid disturbance
Venous Thromboembolism
o Thromboembolic complications remain one of the leading causes
of morbidity and mortality after orthopedic surgery.

o THA, total knee arthroplasty (TKA), and hip and pelvic


fracture surgery have the highest incidence of venous
thromboembolism, including DVT and PE.

o Patients with DVT and PE are at risk for short-term and


long-term morbidity and mortality.
Venous Thromboembolism …

o Patients with symptomatic PE have an 18-fold higher risk of


death than patients with a DVT alone.

o The short-term complications of survivors of acute DVT and PE


include prolonged hospitalization, bleeding complications related
to DVT and PE treatments, local extension of DVT, and further
embolization.

o Long-term complications include post-thrombotic syndrome,


pulmonary hypertension, and recurrent DVT.
Venous Thromboembolism …
Risk factors:
o advanced age greater than 60 years,
o obesity,
o prolonged immobility or bed rest more than 4 days,
o prior history of thromboembolism,
o cancer,
o pre-existing hypercoaguable state
o major surgery.
o procedures lasting more than 30 min,
o use of a tourniquet,
o lower extremity fracture
What to do for VTE
What to do for VTE …
Management

o Pharmacological prophylaxis and the routine use of mechanical


devices such as intermittent pneumatic compression (IPC) have
been shown to decrease the incidence of DVT and PE.

o While mechanical thromboprophylaxis should be considered for


every patient, the use of pharmacological anticoagulants must
be balanced against the risk of major bleeding.
Management …
o For patients at increased risk for DVT but having “normal” bleeding
risk,
 mechanical prophylaxis

 low-dose subcutaneous unfractionated heparin (LUFH),

 warfarin, or

 low-molecular-weight heparin (LMWH)

o Patients at significantly increased risk of bleeding may be managed


with mechanical prophylaxis alone until bleeding risk decreases.
Thank You!!!

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