LUPUS MILIARIS DISSEMINATUS FACIEI Clinical Features • Clinically, it is characterized by discrete, multiple, asymptomatic, monomorphic, erythematous to reddish-brown, dome-shaped papules • involving central area of the face, particularly periorbital area, nasolabial folds, cheeks, and the perioral areas, in a symmetrical distribution • Clinical image of lupus miliaris disseminatus faciei shows • multiple monomorphic, erythematous to reddish- brown, dome-shaped papules on the face, particularly on periorbital area, nasolabial folds, cheeks, and perioral areas Dermoscopic Features • Dermoscopy shows reddish-brown background, multiple ill-defined, discrete, perifollicular, yellow to brown, structureless areas, which represent granulomas. • White or yellow keratotic follicular plugs and perifollicular scales are seen. • Keratotic follicular plugs on dermoscopy are secondary to the follicular hyperkeratosis and lateral pressure on follicles by the surrounding granulomas. • Well-focused linear and branching vessels and white scar- like depigmented areas are present over reddish-brown background • Dermoscopy of lupus miliaris disseminatus faciei shows multiple, ill-defined, discrete, yellow to orange brown, structureless areas (blue arrows), arranged focally in perifollicular distribution.
• White or yellow keratotic follicular
plugs (red arrows), perifollicular scales, well-focused linear and arborizing vessels (yellow arrows) present on over reddish-brown background (white arrows) • Dermoscopy of lupus miliaris disseminatus faciei shows multiple, ill- defined, discrete, yellow to orangish brown, structureless areas (blue arrows), arranged focally around follicles.
• White or yellow keratotic follicular
plugs (red arrows) perifollicular scales, • well-focused linear and arborizing vessels (yellow arrows) seen • over a reddish-brown background (white arrow) • Dermoscopy of lupus miliaris disseminatus faciei shows white scar- like depigmented areas (orange arrows), • structureless areas (blue arrow), • short linear vessels (yellow arrows), and • reddish-brown background (white arrows).
• Perifollicular pigmentation is also
noted (green arrow) Key Points • Multiple, ill-defined, discrete, perifollicular, yellow to brown, structureless areas, which represent granulomas. • Whitish or yellow keratotic follicular plugs and perifollicular scales • Well-focused linear and arborizing vessels are present. GRANULOMA FACIALE Clinical Features • Clinically, it is characterized by occurrence of asymptomatic, single or multiple, reddish-brown, papules, plaques or nodules, primarily on the sun-exposed areas, especially face • Lesions are usually soft, with prominent follicular openings, giving it a characteristic orange peel-like surface. (A) Clinical image of granuloma faciale shows erythematous to violaceous plaque with prominent follicular openings on nose; (B) Clinical image of granuloma faciale shows erythematous to brownish plaque with scaling on the forehead; Dermoscopic Features • It shows pink to reddish-brown background, with some areas of translucent white-gray color. • Vascular inflammation, erythrocyte extravasation, and hemosiderin de- position may contribute to color of lesion. • Whitish streaks in different directions, associated with fairly focused, linear branching vessels are commonly seen. • Prominent follicular orifices or follicular accentuation giving it a “peau d’orange” appearance clinically, corresponding to the intense inflammatory infiltrate of lymphohistiocytes, neutrophils, and numerous eosinophils, in a micronodular arrangement with sparing of adnexal structures of skin. • An amorphous yellowish or yellow-brown or brown area may be present in the center of lesion which has been correlated to the presence of abundance of hemosiderin deposition in these lesions on histopathology • Dermoscopy of granuloma faciale shows pink to reddish-brown background (red arrow), • prominent follicular orifices (green arrows), • areas of translucent white- gray color (blue arrows), • few whitish streaks in different directions (yellow arrow), and • fairly focused, linear branching vessels (white arrows) • Dermoscopy of granuloma faciale shows reddish- brown background (red arrow), • marked follicular accentuation (green arrows), • areas of translucent white- gray color (blue arrows), and • linear branching vessels (white arrows) Key Points • Pink to reddish-brown background, with some areas of translucent white-gray color. • Whitish streaks in different directions, associated with fairly focused, linear branching vessels • Prominent follicular orifices or follicular accentuation giving it a “peau d’orange” appearance • An amorphous yellowish or yellow-brown or brown area may be present in the center of lesion. ERYTHROMELANOSIS FOLLICULARIS FACIEI ET COLLI Clinical Features • A rare disorder described for the first time by Kitamura et al., has onset during early childhood and occurs predominantly in males. • Clinically, it is characterized by presence of sharply demarcated erythema (with or without telangiectasia), reddish-brown patches of hyperpigmentation along with follicular papules present on face, mainly cheeks, preauricular and temporal areas, extending over to involve the submandibular areas of neck (A) Clinical image of erythromelanosis follicularis faciei et colli shows classical triad of • erythema, • hyperpigmentation, and • follicular papules • involving preauricular areas, cheeks, temporal areas, and side of nose (B) Clinical image of erythromelanosis follicularis faciei et colli shows erythema, follicular papules, and hyperpigmentation in a classical distribution over preauricular areas, cheeks, and chin extending on to temples; (C) Erythromelanosis follicularis faciei et colli shows erythema, follicular papules, and hyperpigmentation in a classical distribution over preauricular area and cheek; Dermoscopic Features • It reveals whitish scales, numerous follicular keratotic plugs against a reddish-brown background and telangiectasias, which on histopathology correspond to presence of hyperkeratotic hair follicles, orthokeratosis, dilated infundibula with follicular plugging, and vasodilation and pigmentation of basal layer, respectively. • Gray-blue dots and granules present in the perifollicular and interfollicular areas are seen, especially in subjects with longer durationof disease, and correlate with the presence of pigmentary incontinence and dermal melanophages, respectively Dermoscopic Features • A coiled up or twisted hair retained inside a follicular prominence is usually observed, with an inflamed follicular papule overlying it. • White shiny structures (rosettes) were observed in some patients under polarized light • (D) Dermoscopy of erythromelanosis follicularis faciei et colli shows white scales, mainly perifollicular in distribution (green arrows), numerous follicular keratotic plugs (blue arrows) against a reddish-brown background and telangiectasias (black arrows). • Perifollicular and interfollicular gray-brown dots and granules (peppering) (red arrows). Twisted/coiled hairs (yellow arrow) are also seen • Dermoscopy of erythromelanosis follicularis faciei et colli shows white scales (green arrows), numerous follicular keratotic plugs (blue arrows) against a red-brown background and telangiectasias (black arrows). • Gray-blue dots and granules present in the perifollicular and interfollicular areas (red arrows). • A coiled up or twisted hair retained inside a follicular prominence is observed, withan inflamed follicular papule overlying it (yellow arrows) • Dermoscopy of erythromelanosis follicularis faciei et colli shows white scales (green arrow), numerous follicular keratotic plugs (blue arrows) against a reddish- brown background and telangiectasias (black arrow). • Gray-blue dots and granules present in the perifollicular and interfollicular areas (red arrows). • A coiled up or twisted hair (yellow arrows) and rosettes (white arrow) are noted TOPICAL STEROID-DEPENDENT FACE • It is common facial dermatosis due to the uncontrolled use of topical steroids in India. Dermoscopic Features • Irregularly dilated, branching tortuous vessels almost interconnecting with each other are seen on dermoscopy, but between the larger interconnecting vessels, the smaller nonlinear vessels can be observed. • In addition, red dots, white structureless areas and yellow areas, corresponding to epidermal and dermal atrophy, respectively, and coarse terminal areas are seen. • Features like follicular plugs, follicular pustules, and rosettes are not seen • (A) Dermoscopy of topical steroid-dependent face shows irregularly dilated, branching tortuous vessels almost interconnecting with each other (blue arrows), along with white structureless areas (green arrows) and red dots (yellow arrows) • (B) Dermoscopy of topical steroid-dependent face shows irregularly dilated, branching tortuous vessels (blue arrows), white structureless areas (green arrows), and red dots (yellow arrows) THANK YOU