What is a MITRAL VALVE PROLAPSE?

Mitral valve prolapse, also known as Barlow

syndrome, is a type of heart valve disease in which
the flaps (also called leaflets or cusps) of the mitral
valve become enlarged or stretched. These enlarged
flaps bulge (prolapse) into the left atrium as the heart
contracts with each heartbeat.

A prolapsed mitral valve means that the valve's flaps

do not always fit and close properly between each
beat of the heart, which may cause the valve to leak
blood backward through the valve back to the left
atrium. This condition is called mitral valve
regurgitation.
• MVP occurs when the flaps of the mitral valve bulge back into the left atrium of the heart during its
contraction. While the exact cause remains elusive, several factors contribute to the development of MVP,
including:

• Genetics:
• A family history of MVP increases the risk of developing the condition.

• Connective Tissue Disorders:

• Conditions like Marfan syndrome and Ehlers-Danlos syndrome are associated with weakened
connective tissue, which can affect the mitral valve's structure.

• Structural Changes:
• Age-related degeneration or damage to the valve's collagen can lead to its improper functioning.

• Hormonal Influences:
• Hormones, particularly estrogen, might affect connective tissue strength and contribute to MVP
development.
Some other risk factors for MVP development include:
Graves’ Disease
Ebstein Anomaly
Muscular Dystrophy
Ehlers-Danlos Syndrome
Scoliosis

Advanced medical research undertaken has been able to conclude that the abnormality in the formation of the mitral
valve or its restructuring leads to this condition. This structural difference can be a result of various factors. Though,
the root cause of these factors is still not known. However, they are expected to be closely connected to human
genetics due to disease prevalence in family lines.
Side Effects
and
Management
• While many individuals with MVP remain asymptomatic, others
may experience the following side effects:
• Mitral Regurgitation: The bulging valve may not close properly, leading to blood
flowing backward into the atrium.
• Arrhythmias: Irregular heart rhythms, such as palpitations or atrial fibrillation, might
occur.
• Chest Pain: MVP can cause chest discomfort due to changes in blood flow.
• Endocarditis: The valve's abnormal structure can increase the risk of bacterial
infection.
• Stroke: Blood clots may form due to disrupted blood flow, potentially leading to
stroke.
• Management involves a combination of lifestyle changes, medications,
and in severe cases, surgery:
• Lifestyle: Regular exercise, maintaining a healthy weight, and reducing stress can help
manage symptoms.
• Medications: Beta-blockers or calcium channel blockers can help regulate heart rate and
reduce palpitations.
• Anticoagulants: In cases of blood clot risk, blood thinners might be prescribed.
• Surgery: Surgical intervention might be necessary for severe regurgitation or valve repair.
Treatment For Mitral Valve Prolapse
It may not be necessary for all people suffering from MVP to
undergo treatments as long as it does not result in the
mentioned observable symptoms. The requirement for any MVP
treatment, however, depends on the discretion of the consulting
medical specialist. The Mitral Valve treatment to be followed in
such cases can be the following.

Management of MVP symptoms through beta blockers

prescription.
Anticoagulants may be prescribed to patients with a history of
stroke.
A surgical repair of the mitral valve may be required for an
improved valve function.
Replacement of the mitral valve is another treatment alternative
for patients in acute advanced stages of MVP.

Your optimal treatment plan can be based on several factors

like the patient’s age, history of their health, current medical
conditions, and treatment of other pre-existing issues.
 Trivia time
HAHAHAHA
Didya
knor?
MVP is also known as "click-murmur
syndrome" due to the distinct clicking
sound and heart murmur often
associated with it.
also has many names -----
>

President Bill Clinton was diagnosed with

MVP during his presidency.
 Conclusion:
Mitral Valve Prolapse is a complex cardiac condition with a range
of causes and potential effects. By understanding its underlying
factors, potential side effects, and management strategies,
individuals with MVP can take proactive steps to ensure their
heart health. Ongoing research continues to deepen our
understanding of this condition, providing hope for improved
treatments and outcomes in the future.
References:

Smith, J., et al. (2020). Long-term Outcomes of Mitral Valve Prolapse. Journal of Cardiology,
10(2), 145-150.

Garcia, R., et al. (2021). Genetic and Molecular Insights into Mitral Valve Prolapse. Circulation
Research, 117(6), 586-597.

https://www.slideshare.net/DinaMostafa1/mitral-valve-prolapse-233171527

https://www.metropolisindia.com/blog/preventive-healthcare/mitral-valve-prolapse/