A neonatal transfusion requires determining the volume of packed red blood cells (PRBCs) to administer based on the infant's weight and desired increase in hemoglobin. Generally, transfusing 10-15 mL/kg of PRBCs will raise hemoglobin by 1-2 g/dL, and the volume can also be calculated using an equation that factors in the infant's weight and the PRBC hematocrit of around 60%.
A neonatal transfusion requires determining the volume of packed red blood cells (PRBCs) to administer based on the infant's weight and desired increase in hemoglobin. Generally, transfusing 10-15 mL/kg of PRBCs will raise hemoglobin by 1-2 g/dL, and the volume can also be calculated using an equation that factors in the infant's weight and the PRBC hematocrit of around 60%.
A neonatal transfusion requires determining the volume of packed red blood cells (PRBCs) to administer based on the infant's weight and desired increase in hemoglobin. Generally, transfusing 10-15 mL/kg of PRBCs will raise hemoglobin by 1-2 g/dL, and the volume can also be calculated using an equation that factors in the infant's weight and the PRBC hematocrit of around 60%.
• Once a decision has been made to transfuse PRBCs and a target
hemoglobin or hematocrit has been selected, the following “rules of thumb” can be used to determine the volume to be administered. Transfusion of 10–15 mL/kg of PRBCs will increase hemoglobin levels 1–2 g/dL. One can also calculate the volume of PRBCs to be transfused with the following equation:
• The hematocrit of a unit of PRBCs is around 60 %, depending on the